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Memory formation in old age requires GSK-3β

Glycogen synthase kinase 3β (GSK-3β) is a therapeutic target for various age-related neurodegenerative diseases. It is linked to the two main pathological features of Alzheimer’s disease (AD), tau and amyloid β (Aβ); GSK-3β is a major candidate to pathologically hyperphosphorylate tau and modulate A...

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Detalles Bibliográficos
Autores principales: Koike, Riki, Takaichi, Yuta, Soeda, Yoshiyuki, Takashima, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997123/
https://www.ncbi.nlm.nih.gov/pubmed/36911517
http://dx.doi.org/10.1016/j.nbas.2021.100022