A diet rich in docosahexaenoic acid enhances reactive astrogliosis and ramified microglia morphology in apolipoprotein E epsilon 4-targeted replacement mice

Docosahexaenoic acid (DHA) consumption reduces spatial memory impairment in mice carrying the human apolipoprotein E ε4 (APOE4) allele. The current study evaluated whether astrocyte and microglia morphology contribute to the mechanism of this result. APOE3 and APOE4 mice were fed either a DHA-enrich...

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Detalles Bibliográficos
Autores principales: Chappus-McCendie, Hillary, Poulin, Marc-Antoine, Chouinard-Watkins, Raphaël, Vandal, Milène, Calon, Frédéric, Lauzon, Marc-Antoine, Plourde, Mélanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997137/
https://www.ncbi.nlm.nih.gov/pubmed/36908881
http://dx.doi.org/10.1016/j.nbas.2022.100046

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