Cargando…

Capillary function progressively deteriorates in prodromal Alzheimer’s disease: A longitudinal MRI perfusion study

Cardiovascular risk factors are associated with the development of Alzheimer’s disease (AD), and increasing evidence suggests that cerebral microvascular dysfunction plays a vital role in the disease progression. Using magnetic resonance imaging, we investigated the two-year changes of the cerebral...

Descripción completa

Detalles Bibliográficos
Autores principales:	Madsen, Lasse S., Nielsen, Rune B., Parbo, Peter, Ismail, Rola, Mikkelsen, Irene K., Gottrup, Hanne, Østergaard, Leif, Brooks, David J., Eskildsen, Simon F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997144/ https://www.ncbi.nlm.nih.gov/pubmed/36908896 http://dx.doi.org/10.1016/j.nbas.2022.100035

Ejemplares similares

Impaired perfusion and capillary dysfunction in prodromal Alzheimer's disease
por: Nielsen, Rune B., et al.
Publicado: (2020)

The Effect of 40-Hz Light Therapy on Amyloid Load in Patients with Prodromal and Clinical Alzheimer's Disease
por: Ismail, Rola, et al.
Publicado: (2018)

Low plasma neurofilament light levels associated with raised cortical microglial activation suggest inflammation acts to protect prodromal Alzheimer’s disease
por: Parbo, Peter, et al.
Publicado: (2020)

The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer’s disease: a longitudinal PET study
por: Ismail, Rola, et al.
Publicado: (2020)

Capillary Dysfunction: Its Detection and Causative Role in Dementias and Stroke
por: Østergaard, Leif, et al.
Publicado: (2015)

Bayesian modeling of Dynamic Contrast Enhanced MRI data in cerebral glioma patients improves the diagnostic quality of hemodynamic parameter maps
por: Tietze, Anna, et al.
Publicado: (2018)

Brain perfusion in dementia with Lewy bodies and Alzheimer’s disease: an arterial spin labeling MRI study on prodromal and mild dementia stages
por: Roquet, Daniel, et al.
Publicado: (2016)

Perfusion MRI Derived Indices of Microvascular Shunting and Flow Control Correlate with Tumor Grade and Outcome in Patients with Cerebral Glioma
por: Tietze, Anna, et al.
Publicado: (2015)

Robust estimation of hemo-dynamic parameters in traditional DCE-MRI models
por: Hansen, Mikkel B., et al.
Publicado: (2019)

Sural Nerve Perfusion in Mice
por: Dudele, Anete, et al.
Publicado: (2020)

Capillary transit time heterogeneity and flow-metabolism coupling after traumatic brain injury
por: Østergaard, Leif, et al.
Publicado: (2014)

The roles of cerebral blood flow, capillary transit time heterogeneity, and oxygen tension in brain oxygenation and metabolism
por: Jespersen, Sune N, et al.
Publicado: (2012)

SARS CoV‐2 related microvascular damage and symptoms during and after COVID‐19: Consequences of capillary transit‐time changes, tissue hypoxia and inflammation
por: Østergaard, Leif
Publicado: (2021)

Brief Assessment of Impaired Cognition (BASIC)—Validation of a new dementia case‐finding instrument integrating cognitive assessment with patient and informant report
por: Jørgensen, Kasper, et al.
Publicado: (2019)

Assessment of Perfused Peripapillary Capillaries and Peripapillary Capillary Density Maps in Glaucoma Patients
por: Sefic, Sanja, et al.
Publicado: (2020)

Validity of the Brief Assessment of Impaired Cognition case‐finding instrument for identification of dementia subgroups and staging of dementia
por: Jørgensen, Kasper, et al.
Publicado: (2022)

Appearance of an unusual ring enhancing brain capillary telangiectasia on 3.0T MRI with dynamic susceptibility contrast perfusion
por: Braileanu, Maria, et al.
Publicado: (2020)

Time Perception in Prodromal Alzheimer's Dementia and in Prodromal Dementia With Lewy Bodies
por: Pai, Ming-Chyi, et al.
Publicado: (2021)

FDG PET metabolic signatures distinguishing prodromal DLB and prodromal AD
por: Kantarci, Kejal, et al.
Publicado: (2021)

The Effects of Capillary Transit Time Heterogeneity (CTH) on the Cerebral Uptake of Glucose and Glucose Analogs: Application to FDG and Comparison to Oxygen Uptake
por: Angleys, Hugo, et al.
Publicado: (2016)

Neuromelanin and T(2)*-MRI for the assessment of genetically at-risk, prodromal, and symptomatic Parkinson’s disease
por: Ben Bashat, Dafna, et al.
Publicado: (2022)

Peripheral capillary non-perfusion in asymptomatic Waldenström's macroglobulinemia
por: Koutsandrea, Chryssanthi, et al.
Publicado: (2010)

Spatial statistical modelling of capillary non-perfusion in the retina
por: MacCormick, Ian J. C., et al.
Publicado: (2017)

Understanding the schizophrenia prodrome
por: George, Manju, et al.
Publicado: (2017)

The prodromes of Parkinson's disease
por: Rees, Richard Nathaniel, et al.
Publicado: (2018)

Brain capillary transit time heterogeneity in healthy volunteers measured by dynamic contrast‐enhanced T(1)‐weighted perfusion MRI
por: Larsson, Henrik B.W., et al.
Publicado: (2016)

Perfusion Magnetic Resonance Imaging: A Comprehensive Update on Principles and Techniques
por: Jahng, Geon-Ho, et al.
Publicado: (2014)

Arterial spin labeled MRI in prodromal Alzheimer's disease: A multi-site study()
por: Wang, Ze, et al.
Publicado: (2013)

Association of EEG, MRI, and regional blood flow biomarkers is predictive of prodromal Alzheimer’s disease
por: Moretti, Davide Vito
Publicado: (2015)

A deep learning MRI approach outperforms other biomarkers of prodromal Alzheimer’s disease
por: Feng, Xinyang, et al.
Publicado: (2022)

Cerebral small vessel disease: Capillary pathways to stroke and cognitive decline
por: Østergaard, Leif, et al.
Publicado: (2015)

The effects of capillary dysfunction on oxygen and glucose extraction in diabetic neuropathy
por: Østergaard, Leif, et al.
Publicado: (2014)

The role of capillary transit time heterogeneity in myocardial oxygenation and ischemic heart disease
por: Østergaard, Leif, et al.
Publicado: (2014)

The schizophrenia prodrome: promise for prevention
por: Cornblatt, Barbara
Publicado: (2001)

The Concept of Prodromal Parkinson’s Disease
por: Mahlknecht, Philipp, et al.
Publicado: (2015)

Editorial: Prodromal Parkinson's Disease
por: Crosiers, David, et al.
Publicado: (2021)

Hippocampal Atrophy Following Subarachnoid Hemorrhage Correlates with Disruption of Astrocyte Morphology and Capillary Coverage by AQP4
por: Anzabi, Maryam, et al.
Publicado: (2018)

MRI-based Alzheimer’s disease-resemblance atrophy index in the detection of preclinical and prodromal Alzheimer’s disease
por: Liu, Wanting, et al.
Publicado: (2021)

A comparison of prediction approaches for identifying prodromal Parkinson disease
por: Warden, Mark N., et al.
Publicado: (2021)

Prevalence and duration of non‐motor symptoms in prodromal Parkinson's disease
por: Durcan, R., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ksfbam0dtj6b467cevg935qkjj