Hearing loss is associated with gray matter differences in older adults at risk for and with Alzheimer’s disease

Using data from the COMPASS-ND study we investigated associations between hearing loss and hippocampal volume as well as cortical thickness in older adults with subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer’s dementia (AD). SCD participants with greater pure-tone...

Descripción completa

Detalles Bibliográficos
Autores principales: Giroud, N., Pichora-Fuller, M.K., Mick, P., Wittich, W., Al-Yawer, F., Rehan, S., Orange, J.B., Phillips, N.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997162/
https://www.ncbi.nlm.nih.gov/pubmed/36911511
http://dx.doi.org/10.1016/j.nbas.2021.100018
_version_ 1784903201816838144
author Giroud, N.
Pichora-Fuller, M.K.
Mick, P.
Wittich, W.
Al-Yawer, F.
Rehan, S.
Orange, J.B.
Phillips, N.A.
author_facet Giroud, N.
Pichora-Fuller, M.K.
Mick, P.
Wittich, W.
Al-Yawer, F.
Rehan, S.
Orange, J.B.
Phillips, N.A.
author_sort Giroud, N.
collection PubMed
description Using data from the COMPASS-ND study we investigated associations between hearing loss and hippocampal volume as well as cortical thickness in older adults with subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer’s dementia (AD). SCD participants with greater pure-tone hearing loss exhibited lower hippocampal volume, but more cortical thickness in the left superior temporal gyrus and right pars opercularis. Greater speech-in-noise reception thresholds were associated with lower cortical thickness bilaterally across much of the cortex in AD. The AD group also showed a trend towards worse speech-in-noise thresholds compared to the SCD group.
format Online
Article
Text
id pubmed-9997162
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-99971622023-03-09 Hearing loss is associated with gray matter differences in older adults at risk for and with Alzheimer’s disease Giroud, N. Pichora-Fuller, M.K. Mick, P. Wittich, W. Al-Yawer, F. Rehan, S. Orange, J.B. Phillips, N.A. Aging Brain Article Using data from the COMPASS-ND study we investigated associations between hearing loss and hippocampal volume as well as cortical thickness in older adults with subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer’s dementia (AD). SCD participants with greater pure-tone hearing loss exhibited lower hippocampal volume, but more cortical thickness in the left superior temporal gyrus and right pars opercularis. Greater speech-in-noise reception thresholds were associated with lower cortical thickness bilaterally across much of the cortex in AD. The AD group also showed a trend towards worse speech-in-noise thresholds compared to the SCD group. Elsevier 2021-06-28 /pmc/articles/PMC9997162/ /pubmed/36911511 http://dx.doi.org/10.1016/j.nbas.2021.100018 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Giroud, N.
Pichora-Fuller, M.K.
Mick, P.
Wittich, W.
Al-Yawer, F.
Rehan, S.
Orange, J.B.
Phillips, N.A.
Hearing loss is associated with gray matter differences in older adults at risk for and with Alzheimer’s disease
title Hearing loss is associated with gray matter differences in older adults at risk for and with Alzheimer’s disease
title_full Hearing loss is associated with gray matter differences in older adults at risk for and with Alzheimer’s disease
title_fullStr Hearing loss is associated with gray matter differences in older adults at risk for and with Alzheimer’s disease
title_full_unstemmed Hearing loss is associated with gray matter differences in older adults at risk for and with Alzheimer’s disease
title_short Hearing loss is associated with gray matter differences in older adults at risk for and with Alzheimer’s disease
title_sort hearing loss is associated with gray matter differences in older adults at risk for and with alzheimer’s disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997162/
https://www.ncbi.nlm.nih.gov/pubmed/36911511
http://dx.doi.org/10.1016/j.nbas.2021.100018
work_keys_str_mv AT giroudn hearinglossisassociatedwithgraymatterdifferencesinolderadultsatriskforandwithalzheimersdisease
AT pichorafullermk hearinglossisassociatedwithgraymatterdifferencesinolderadultsatriskforandwithalzheimersdisease
AT mickp hearinglossisassociatedwithgraymatterdifferencesinolderadultsatriskforandwithalzheimersdisease
AT wittichw hearinglossisassociatedwithgraymatterdifferencesinolderadultsatriskforandwithalzheimersdisease
AT alyawerf hearinglossisassociatedwithgraymatterdifferencesinolderadultsatriskforandwithalzheimersdisease
AT rehans hearinglossisassociatedwithgraymatterdifferencesinolderadultsatriskforandwithalzheimersdisease
AT orangejb hearinglossisassociatedwithgraymatterdifferencesinolderadultsatriskforandwithalzheimersdisease
AT phillipsna hearinglossisassociatedwithgraymatterdifferencesinolderadultsatriskforandwithalzheimersdisease

Ejemplares similares