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Functional near infrared spectroscopy activation during an executive function task differs between healthy older and younger adults
BACKGROUND: Healthy aging can include declines in processing speed and executive function. Further research is needed to characterize the neurobiological underpinnings of these cognitive changes in older adulthood. The current study used functional near infrared spectroscopy (fNIRS), an optical neur...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997178/ https://www.ncbi.nlm.nih.gov/pubmed/36908882 http://dx.doi.org/10.1016/j.nbas.2022.100029 |
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author | Kwan, Heather Scarapicchia, Vanessa Halliday, Drew MacDonald, Stuart Gawryluk, Jodie R. |
author_facet | Kwan, Heather Scarapicchia, Vanessa Halliday, Drew MacDonald, Stuart Gawryluk, Jodie R. |
author_sort | Kwan, Heather |
collection | PubMed |
description | BACKGROUND: Healthy aging can include declines in processing speed and executive function. Further research is needed to characterize the neurobiological underpinnings of these cognitive changes in older adulthood. The current study used functional near infrared spectroscopy (fNIRS), an optical neuroimaging technique, to examine differences in cerebral oxygenation between healthy older adults (OA) and younger adults (YA) during a measure of cognitive interference. METHODS: Thirty-four participants were sampled from two age groups: YA (mean age = 28.1 years, SD = 2.8, F = 9) and OA (mean age = 70.9 years, SD = 5.4, F = 9). Participants completed the Multi-Source Interference Task (MSIT), a measure of executive function with high and low-demand conditions, while undergoing fNIRS recordings using a TechEn CW6 system with 34-source-detector channels, situated over the prefrontal cortex. Functional activation patterns, accuracy, and reaction time were compared between and within groups for each condition. RESULTS: Behaviourally, during the control condition, OA and YA had comparable accuracy, although OA had significantly slower reaction times than YA. During the interference condition, OA had significantly lower accuracy and slower reaction times than YA. Results demonstrated a significant difference between groups with an age-related increase in HbO for OA in both conditions (p < 0.05). Within groups, OA showed greater activation during the control condition, while YA demonstrated greater activation during the interference condition. CONCLUSIONS: The findings suggest that OA recruit additional neural resources to achieve similar behavioural performance during low-level cognitive interference, but that compensation in OA may be insufficient to support behavioural performance at higher levels of interference. |
format | Online Article Text |
id | pubmed-9997178 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-99971782023-03-09 Functional near infrared spectroscopy activation during an executive function task differs between healthy older and younger adults Kwan, Heather Scarapicchia, Vanessa Halliday, Drew MacDonald, Stuart Gawryluk, Jodie R. Aging Brain Article BACKGROUND: Healthy aging can include declines in processing speed and executive function. Further research is needed to characterize the neurobiological underpinnings of these cognitive changes in older adulthood. The current study used functional near infrared spectroscopy (fNIRS), an optical neuroimaging technique, to examine differences in cerebral oxygenation between healthy older adults (OA) and younger adults (YA) during a measure of cognitive interference. METHODS: Thirty-four participants were sampled from two age groups: YA (mean age = 28.1 years, SD = 2.8, F = 9) and OA (mean age = 70.9 years, SD = 5.4, F = 9). Participants completed the Multi-Source Interference Task (MSIT), a measure of executive function with high and low-demand conditions, while undergoing fNIRS recordings using a TechEn CW6 system with 34-source-detector channels, situated over the prefrontal cortex. Functional activation patterns, accuracy, and reaction time were compared between and within groups for each condition. RESULTS: Behaviourally, during the control condition, OA and YA had comparable accuracy, although OA had significantly slower reaction times than YA. During the interference condition, OA had significantly lower accuracy and slower reaction times than YA. Results demonstrated a significant difference between groups with an age-related increase in HbO for OA in both conditions (p < 0.05). Within groups, OA showed greater activation during the control condition, while YA demonstrated greater activation during the interference condition. CONCLUSIONS: The findings suggest that OA recruit additional neural resources to achieve similar behavioural performance during low-level cognitive interference, but that compensation in OA may be insufficient to support behavioural performance at higher levels of interference. Elsevier 2022-01-19 /pmc/articles/PMC9997178/ /pubmed/36908882 http://dx.doi.org/10.1016/j.nbas.2022.100029 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Kwan, Heather Scarapicchia, Vanessa Halliday, Drew MacDonald, Stuart Gawryluk, Jodie R. Functional near infrared spectroscopy activation during an executive function task differs between healthy older and younger adults |
title | Functional near infrared spectroscopy activation during an executive function task differs between healthy older and younger adults |
title_full | Functional near infrared spectroscopy activation during an executive function task differs between healthy older and younger adults |
title_fullStr | Functional near infrared spectroscopy activation during an executive function task differs between healthy older and younger adults |
title_full_unstemmed | Functional near infrared spectroscopy activation during an executive function task differs between healthy older and younger adults |
title_short | Functional near infrared spectroscopy activation during an executive function task differs between healthy older and younger adults |
title_sort | functional near infrared spectroscopy activation during an executive function task differs between healthy older and younger adults |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997178/ https://www.ncbi.nlm.nih.gov/pubmed/36908882 http://dx.doi.org/10.1016/j.nbas.2022.100029 |
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