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Age-related reduction in brain ACE-2 is not exacerbated by Alzheimer’s disease pathology in mouse models of Alzheimer’s disease

An imbalance in the circulatory and organ-specific renin-angiotensin system (RAS) pathways is associated with age-related dysfunction and disease including cardiovascular burden and more recently Alzheimer’s disease (AD). It is currently unclear whether an age-associated imbalance in components of t...

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Detalles Bibliográficos
Autores principales: MacLachlan, Robert, Evans, Charles E., Chai, Siew Yeen, Good, Mark A., Kehoe, Patrick Gavin, Miners, J. Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997187/
https://www.ncbi.nlm.nih.gov/pubmed/36911263
http://dx.doi.org/10.1016/j.nbas.2022.100062