LOXL1 and LOXL4 are novel target genes of the Zn(2+)-bound form of ZEB1 and play a crucial role in the acceleration of invasive events in triple-negative breast cancer cells

BACKGROUND: EMT has been proposed to be a crucial early event in cancer metastasis. EMT is rigidly regulated by the action of several EMT-core transcription factors, particularly ZEB1. We previously revealed an unusual role of ZEB1 in the S100A8/A9-mediated metastasis in breast cancer cells that exp...

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Detalles Bibliográficos
Autores principales: Hirabayashi, Daisuke, Yamamoto, Ken-ichi, Maruyama, Akihiro, Tomonobu, Nahoko, Kinoshita, Rie, Chen, Youyi, Komalasari, Ni Luh Gede Yoni, Murata, Hitoshi, Gohara, Yuma, Jiang, Fan, Zhou, Jin, Ruma, I Made Winarsa, Sumardika, I Wayan, Yamauchi, Akira, Kuribayashi, Futoshi, Toyooka, Shinichi, Inoue, Yusuke, Sakaguchi, Masakiyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997211/
https://www.ncbi.nlm.nih.gov/pubmed/36910659
http://dx.doi.org/10.3389/fonc.2023.1142886

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