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The Use of Systemic Inflammatory Response Syndrome (SIRS) and Elevated Liver Enzymes as Predictive Factors of Gangrenous Cholecystitis: A Case Report

Gangrenous cholecystitis is a severe complication of acute cholecystitis. It is often found incidentally during laparoscopic cholecystectomy or during conversion to open surgery and diagnosed with subsequent pathological analysis. While intraoperative diagnosis is typically through direct visualizat...

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Autores principales: Pyfrom, Dejeau P, Ali, Muhammad Zain, Ghouse, Farhana, Ganesh, Vaishnavi, Tiesenga, Frederick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997421/
https://www.ncbi.nlm.nih.gov/pubmed/36909064
http://dx.doi.org/10.7759/cureus.34727
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author Pyfrom, Dejeau P
Ali, Muhammad Zain
Ghouse, Farhana
Ganesh, Vaishnavi
Tiesenga, Frederick
author_facet Pyfrom, Dejeau P
Ali, Muhammad Zain
Ghouse, Farhana
Ganesh, Vaishnavi
Tiesenga, Frederick
author_sort Pyfrom, Dejeau P
collection PubMed
description Gangrenous cholecystitis is a severe complication of acute cholecystitis. It is often found incidentally during laparoscopic cholecystectomy or during conversion to open surgery and diagnosed with subsequent pathological analysis. While intraoperative diagnosis is typically through direct visualization of the gallbladder, specific diagnostic modalities may guide physicians toward an earlier diagnosis. Surgical intervention and a more aggressive approach are often needed to prevent the advancement of the disease and its catastrophic complications. This case report illustrates the distinct risk factors predisposing a patient to develop gangrenous cholecystitis. Comorbidities such as hypertension, coronary artery disease, age, the relevance of the SIRS criteria, and elevated liver enzymes are explored as predictive factors in a patient with gangrenous cholecystitis. 
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spelling pubmed-99974212023-03-10 The Use of Systemic Inflammatory Response Syndrome (SIRS) and Elevated Liver Enzymes as Predictive Factors of Gangrenous Cholecystitis: A Case Report Pyfrom, Dejeau P Ali, Muhammad Zain Ghouse, Farhana Ganesh, Vaishnavi Tiesenga, Frederick Cureus Pathology Gangrenous cholecystitis is a severe complication of acute cholecystitis. It is often found incidentally during laparoscopic cholecystectomy or during conversion to open surgery and diagnosed with subsequent pathological analysis. While intraoperative diagnosis is typically through direct visualization of the gallbladder, specific diagnostic modalities may guide physicians toward an earlier diagnosis. Surgical intervention and a more aggressive approach are often needed to prevent the advancement of the disease and its catastrophic complications. This case report illustrates the distinct risk factors predisposing a patient to develop gangrenous cholecystitis. Comorbidities such as hypertension, coronary artery disease, age, the relevance of the SIRS criteria, and elevated liver enzymes are explored as predictive factors in a patient with gangrenous cholecystitis.  Cureus 2023-02-07 /pmc/articles/PMC9997421/ /pubmed/36909064 http://dx.doi.org/10.7759/cureus.34727 Text en Copyright © 2023, Pyfrom et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Pyfrom, Dejeau P
Ali, Muhammad Zain
Ghouse, Farhana
Ganesh, Vaishnavi
Tiesenga, Frederick
The Use of Systemic Inflammatory Response Syndrome (SIRS) and Elevated Liver Enzymes as Predictive Factors of Gangrenous Cholecystitis: A Case Report
title The Use of Systemic Inflammatory Response Syndrome (SIRS) and Elevated Liver Enzymes as Predictive Factors of Gangrenous Cholecystitis: A Case Report
title_full The Use of Systemic Inflammatory Response Syndrome (SIRS) and Elevated Liver Enzymes as Predictive Factors of Gangrenous Cholecystitis: A Case Report
title_fullStr The Use of Systemic Inflammatory Response Syndrome (SIRS) and Elevated Liver Enzymes as Predictive Factors of Gangrenous Cholecystitis: A Case Report
title_full_unstemmed The Use of Systemic Inflammatory Response Syndrome (SIRS) and Elevated Liver Enzymes as Predictive Factors of Gangrenous Cholecystitis: A Case Report
title_short The Use of Systemic Inflammatory Response Syndrome (SIRS) and Elevated Liver Enzymes as Predictive Factors of Gangrenous Cholecystitis: A Case Report
title_sort use of systemic inflammatory response syndrome (sirs) and elevated liver enzymes as predictive factors of gangrenous cholecystitis: a case report
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997421/
https://www.ncbi.nlm.nih.gov/pubmed/36909064
http://dx.doi.org/10.7759/cureus.34727
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