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LGI3/2–ADAM23 interactions cluster Kv1 channels in myelinated axons to regulate refractory period
Along myelinated axons, Shaker-type potassium channels (Kv1) accumulate at high density in the juxtaparanodal region, directly adjacent to the paranodal axon–glia junctions that flank the nodes of Ranvier. However, the mechanisms that control the clustering of Kv1 channels, as well as their function...
Autores principales: | Kozar-Gillan, Nina, Velichkova, Atanaska, Kanatouris, George, Eshed-Eisenbach, Yael, Steel, Gavin, Jaegle, Martine, Aunin, Eerik, Peles, Elior, Torsney, Carole, Meijer, Dies N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997507/ https://www.ncbi.nlm.nih.gov/pubmed/36828548 http://dx.doi.org/10.1083/jcb.202211031 |
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