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Electrochemotherapy with bleomycin as an effective local treatment for Kaposi’s sarcoma: a case report
An elderly female patient with a long-standing history of Kaposi’s sarcoma of the lower limbs was referred to the Surgical Department after the subsequential failure of multiple lines of systemic chemotherapy. The patient was also complaining of increasing symptoms including intractable pruritus, wh...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997621/ https://www.ncbi.nlm.nih.gov/pubmed/36730383 http://dx.doi.org/10.1097/CAD.0000000000001427 |
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author | Niccolò, Allievi Elena, Manzo Nadiane, Paderno Barbara, Merelli Gianlorenzo, Imberti Dario, Piazzalunga |
author_facet | Niccolò, Allievi Elena, Manzo Nadiane, Paderno Barbara, Merelli Gianlorenzo, Imberti Dario, Piazzalunga |
author_sort | Niccolò, Allievi |
collection | PubMed |
description | An elderly female patient with a long-standing history of Kaposi’s sarcoma of the lower limbs was referred to the Surgical Department after the subsequential failure of multiple lines of systemic chemotherapy. The patient was also complaining of increasing symptoms including intractable pruritus, which negatively impacted her quality of life. She underwent palliative electrochemotherapy with bleomycin (15 g/m(2)) on the sarcomatous lesions of the left foot and ankle, which lead to complete clinical response and resolution of symptoms; no adverse events were reported. Electrochemotherapy is a valid option in the palliative treatment of Kaposi’s sarcoma, as it may lead to satisfactory clinical response and symptom control. |
format | Online Article Text |
id | pubmed-9997621 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-99976212023-03-09 Electrochemotherapy with bleomycin as an effective local treatment for Kaposi’s sarcoma: a case report Niccolò, Allievi Elena, Manzo Nadiane, Paderno Barbara, Merelli Gianlorenzo, Imberti Dario, Piazzalunga Anticancer Drugs Case Reports An elderly female patient with a long-standing history of Kaposi’s sarcoma of the lower limbs was referred to the Surgical Department after the subsequential failure of multiple lines of systemic chemotherapy. The patient was also complaining of increasing symptoms including intractable pruritus, which negatively impacted her quality of life. She underwent palliative electrochemotherapy with bleomycin (15 g/m(2)) on the sarcomatous lesions of the left foot and ankle, which lead to complete clinical response and resolution of symptoms; no adverse events were reported. Electrochemotherapy is a valid option in the palliative treatment of Kaposi’s sarcoma, as it may lead to satisfactory clinical response and symptom control. Lippincott Williams & Wilkins 2023-04 2022-11-18 /pmc/articles/PMC9997621/ /pubmed/36730383 http://dx.doi.org/10.1097/CAD.0000000000001427 Text en Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Case Reports Niccolò, Allievi Elena, Manzo Nadiane, Paderno Barbara, Merelli Gianlorenzo, Imberti Dario, Piazzalunga Electrochemotherapy with bleomycin as an effective local treatment for Kaposi’s sarcoma: a case report |
title | Electrochemotherapy with bleomycin as an effective local treatment for Kaposi’s sarcoma: a case report |
title_full | Electrochemotherapy with bleomycin as an effective local treatment for Kaposi’s sarcoma: a case report |
title_fullStr | Electrochemotherapy with bleomycin as an effective local treatment for Kaposi’s sarcoma: a case report |
title_full_unstemmed | Electrochemotherapy with bleomycin as an effective local treatment for Kaposi’s sarcoma: a case report |
title_short | Electrochemotherapy with bleomycin as an effective local treatment for Kaposi’s sarcoma: a case report |
title_sort | electrochemotherapy with bleomycin as an effective local treatment for kaposi’s sarcoma: a case report |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997621/ https://www.ncbi.nlm.nih.gov/pubmed/36730383 http://dx.doi.org/10.1097/CAD.0000000000001427 |
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