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Electrochemotherapy with bleomycin as an effective local treatment for Kaposi’s sarcoma: a case report

An elderly female patient with a long-standing history of Kaposi’s sarcoma of the lower limbs was referred to the Surgical Department after the subsequential failure of multiple lines of systemic chemotherapy. The patient was also complaining of increasing symptoms including intractable pruritus, wh...

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Autores principales: Niccolò, Allievi, Elena, Manzo, Nadiane, Paderno, Barbara, Merelli, Gianlorenzo, Imberti, Dario, Piazzalunga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997621/
https://www.ncbi.nlm.nih.gov/pubmed/36730383
http://dx.doi.org/10.1097/CAD.0000000000001427
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author Niccolò, Allievi
Elena, Manzo
Nadiane, Paderno
Barbara, Merelli
Gianlorenzo, Imberti
Dario, Piazzalunga
author_facet Niccolò, Allievi
Elena, Manzo
Nadiane, Paderno
Barbara, Merelli
Gianlorenzo, Imberti
Dario, Piazzalunga
author_sort Niccolò, Allievi
collection PubMed
description An elderly female patient with a long-standing history of Kaposi’s sarcoma of the lower limbs was referred to the Surgical Department after the subsequential failure of multiple lines of systemic chemotherapy. The patient was also complaining of increasing symptoms including intractable pruritus, which negatively impacted her quality of life. She underwent palliative electrochemotherapy with bleomycin (15 g/m(2)) on the sarcomatous lesions of the left foot and ankle, which lead to complete clinical response and resolution of symptoms; no adverse events were reported. Electrochemotherapy is a valid option in the palliative treatment of Kaposi’s sarcoma, as it may lead to satisfactory clinical response and symptom control.
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spelling pubmed-99976212023-03-09 Electrochemotherapy with bleomycin as an effective local treatment for Kaposi’s sarcoma: a case report Niccolò, Allievi Elena, Manzo Nadiane, Paderno Barbara, Merelli Gianlorenzo, Imberti Dario, Piazzalunga Anticancer Drugs Case Reports An elderly female patient with a long-standing history of Kaposi’s sarcoma of the lower limbs was referred to the Surgical Department after the subsequential failure of multiple lines of systemic chemotherapy. The patient was also complaining of increasing symptoms including intractable pruritus, which negatively impacted her quality of life. She underwent palliative electrochemotherapy with bleomycin (15 g/m(2)) on the sarcomatous lesions of the left foot and ankle, which lead to complete clinical response and resolution of symptoms; no adverse events were reported. Electrochemotherapy is a valid option in the palliative treatment of Kaposi’s sarcoma, as it may lead to satisfactory clinical response and symptom control. Lippincott Williams & Wilkins 2023-04 2022-11-18 /pmc/articles/PMC9997621/ /pubmed/36730383 http://dx.doi.org/10.1097/CAD.0000000000001427 Text en Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Reports
Niccolò, Allievi
Elena, Manzo
Nadiane, Paderno
Barbara, Merelli
Gianlorenzo, Imberti
Dario, Piazzalunga
Electrochemotherapy with bleomycin as an effective local treatment for Kaposi’s sarcoma: a case report
title Electrochemotherapy with bleomycin as an effective local treatment for Kaposi’s sarcoma: a case report
title_full Electrochemotherapy with bleomycin as an effective local treatment for Kaposi’s sarcoma: a case report
title_fullStr Electrochemotherapy with bleomycin as an effective local treatment for Kaposi’s sarcoma: a case report
title_full_unstemmed Electrochemotherapy with bleomycin as an effective local treatment for Kaposi’s sarcoma: a case report
title_short Electrochemotherapy with bleomycin as an effective local treatment for Kaposi’s sarcoma: a case report
title_sort electrochemotherapy with bleomycin as an effective local treatment for kaposi’s sarcoma: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997621/
https://www.ncbi.nlm.nih.gov/pubmed/36730383
http://dx.doi.org/10.1097/CAD.0000000000001427
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