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Modeling the progression of Type 2 diabetes with underlying obesity

Environmentally induced or epigenetic-related beta-cell dysfunction and insulin resistance play a critical role in the progression to diabetes. We developed a mathematical modeling framework capable of studying the progression to diabetes incorporating various diabetogenic factors. Considering the h...

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Detalles Bibliográficos
Autores principales: Yang, Boya, Li, Jiaxu, Haller, Michael J., Schatz, Desmond A., Rong, Libin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997875/
https://www.ncbi.nlm.nih.gov/pubmed/36848379
http://dx.doi.org/10.1371/journal.pcbi.1010914