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Testicular histone hyperacetylation in mice by valproic acid administration affects the next generation by changes in sperm DNA methylation
Various studies have described epigenetic inheritance through sperms. However, the detailed mechanisms remain unclear. In this study, we focused on DNA methylation in mice treated with valproic acid (VPA), an inducer of epigenomic changes, and analyzed the treatment effects on the sperm from the nex...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997898/ https://www.ncbi.nlm.nih.gov/pubmed/36893188 http://dx.doi.org/10.1371/journal.pone.0282898 |