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Why does the X chromosome lag behind autosomes in GWAS findings?

The X-chromosome is among the largest human chromosomes. It differs from autosomes by a number of important features including hemizygosity in males, an almost complete inactivation of one copy in females, and unique patterns of recombination. We used data from the Catalog of Published Genome Wide A...

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Detalles Bibliográficos
Autores principales: Gorlov, Ivan P., Amos, Christopher I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997976/
https://www.ncbi.nlm.nih.gov/pubmed/36848382
http://dx.doi.org/10.1371/journal.pgen.1010472