Cytochrome P450 2C19 Polymorphisms and Its Association With Major Adverse Cardiac Events in Post-coronary Intervention Patients on Clopidogrel in the Tertiary Care Center

Background Clopidogrel has become essential in managing coronary artery disease and other atherothrombotic diseases. It is an inactive prodrug that needs biotransformation in the liver by various cytochrome P (CYP) 450 isoenzymes for its active metabolite formation. However, 4-30% of patients on clo...

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Detalles Bibliográficos
Autores principales: Kambhampati, Nikhil Teja, Ahamed, Hisham, K.K, Velayudhan, David, Sachin, Hakeem, Sai chandra, Pillai, Gopalakrishna, Kartha, Niveditha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Cardiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998108/
https://www.ncbi.nlm.nih.gov/pubmed/36913219
http://dx.doi.org/10.7759/cureus.34737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998108/
https://www.ncbi.nlm.nih.gov/pubmed/36913219
http://dx.doi.org/10.7759/cureus.34737

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