Cargando…

Cytochrome P450 2C19 Polymorphisms and Its Association With Major Adverse Cardiac Events in Post-coronary Intervention Patients on Clopidogrel in the Tertiary Care Center

Background Clopidogrel has become essential in managing coronary artery disease and other atherothrombotic diseases. It is an inactive prodrug that needs biotransformation in the liver by various cytochrome P (CYP) 450 isoenzymes for its active metabolite formation. However, 4-30% of patients on clo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kambhampati, Nikhil Teja, Ahamed, Hisham, K.K, Velayudhan, David, Sachin, Hakeem, Sai chandra, Pillai, Gopalakrishna, Kartha, Niveditha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cureus 2023
Materias:	Cardiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998108/ https://www.ncbi.nlm.nih.gov/pubmed/36913219 http://dx.doi.org/10.7759/cureus.34737

Ejemplares similares

The Association Between Microalbuminuria and QTc Prolongation in Patients With Type 2 Diabetes Mellitus: A Single-Centre Study From South India
por: Dominic, Solomon K, et al.
Publicado: (2023)

Left Ventricular Diastolic Dysfunction in Type 2 Diabetes Mellitus: A Single-Centre Observational Study From a Tertiary Care Hospital in South India
por: CM, Wazeem, et al.
Publicado: (2023)

Implications of Pharmacogenetic Testing for Clopidogrel Therapy in a Tertiary Healthcare Hospital in North India
por: Amarapalli, Jayachandra, et al.
Publicado: (2023)

Ticagrelor Versus Clopidogrel in Patients With Acute Coronary Syndrome and on Dialysis: A Meta-Analysis
por: Chenna, Venkata Sai Harshabhargav, et al.
Publicado: (2023)

An Examination of Clopidogrel in the Treatment of Coronary Microvascular Disease
por: Iskandar, Nicholas P, et al.
Publicado: (2022)

Microalbuminuria as an Independent Risk Factor for Developing Concentric Left Ventricular Hypertrophy in Primary Hypertension: A Single-Center Observational Study From South India
por: Moidu, Sayyid, et al.
Publicado: (2022)

A Case of Hypoglycemia With Concomitant Use of a Sulfonylurea and Clopidogrel
por: Ruiz, Brent, et al.
Publicado: (2022)

Acute Multiple In-Stent Thromboses in a Patient With Clopidogrel-Fluconazole Interaction
por: El Khoury, Antoine, et al.
Publicado: (2022)

Association of Cytochrome P450 Genetic Variants with Clopidogrel Resistance and Outcomes in Acute Ischemic Stroke
por: Yi, Xingyang, et al.
Publicado: (2016)

Clopidogrel-Associated Interstitial Lung Disease: A Case Report and Literature Review
por: Abro, Sheeraz, et al.
Publicado: (2022)

Cytochrome P450 2C19 Polymorphism is Associated with Reduced Clopidogrel Response in Cerebrovascular Disease
por: Lee, Jun-Beom, et al.
Publicado: (2011)

Cytochrome P450 3A4*22, PPAR-α, and ARNT polymorphisms and clopidogrel response
por: Kreutz, Rolf P, et al.
Publicado: (2013)

A Rare Case of Clopidogrel-Induced Migratory Polyarthritis in a Patient With Recent Myocardial Infarction
por: Khan, Zahid, et al.
Publicado: (2022)

Effects of Triflusal and Clopidogrel on the Secondary Prevention of Stroke Based on Cytochrome P450 2C19 Genotyping
por: Han, Sang Won, et al.
Publicado: (2017)

Influence of paraoxonase-1 Q192R and cytochrome P450 2C19 polymorphisms on clopidogrel response
por: Kreutz, Rolf P, et al.
Publicado: (2012)

Influence of cytochrome P450 polymorphisms on the antiplatelet effects of prasugrel in patients with non-cardioembolic stroke previously treated with clopidogrel
por: Kitazono, Takanari, et al.
Publicado: (2018)

Cytochrome P450 enzyme-mediated auto-enhanced photodynamic cancer therapy of co-nanoassembly between clopidogrel and photosensitizer
por: Wang, Qiu, et al.
Publicado: (2020)

Ticagrelor-induced Angioedema After Percutaneous Coronary Intervention in a Patient with a History of Ischemic Stroke and Low Response to Clopidogrel: A Rare Dilemma
por: Piranavan, Paramarajan, et al.
Publicado: (2018)

Reducing All-cause 30-day Hospital Readmissions for Patients Presenting with Acute Heart Failure Exacerbations: A Quality Improvement Initiative
por: Nair, Raunak, et al.
Publicado: (2020)

Impact of Cytochrome P450 2C19* 2 and * 3 on Clopidogrel Loading Dose in Saudi Patients with Acute Coronary Syndrome
por: Khalaf, Hassan, et al.
Publicado: (2016)

Clopidogrel preventive effect based on cytochrome P450 2C19 genotype in ischaemic stroke: protocol for multicentre observational study
por: Song, Tae-Jin, et al.
Publicado: (2020)

The Cytochrome P450 Homepage
por: Nelson, David R
Publicado: (2009)

Real-world comparison of clopidogrel, prasugrel and ticagrelor in patients undergoing primary percutaneous coronary intervention
por: Krishnamurthy, Arvindra, et al.
Publicado: (2019)

Probing the Role of the Hinge Segment of Cytochrome P450 Oxidoreductase in the Interaction with Cytochrome P450
por: Campelo, Diana, et al.
Publicado: (2018)

Interventions to Decrease Overuse of Cardiac Monitoring (Telemetry) When Transitioning from the Intensive Care Unit to the Regular Nursing Floor
por: Chahine, Johnny, et al.
Publicado: (2019)

Effects of Cytochrome P450 2C19 and Paraoxonase 1 Polymorphisms on Antiplatelet Response to Clopidogrel Therapy in Patients with Coronary Artery Disease
por: Tresukosol, Damrus, et al.
Publicado: (2014)

The FMN “140s Loop” of Cytochrome P450 Reductase Controls Electron Transfer to Cytochrome P450
por: Rwere, Freeborn, et al.
Publicado: (2021)

Measurement of Occupational Eye and Thyroid Radiation Doses in Pediatric Interventional Cardiologists at a Tertiary Hospital
por: Khafaji, Mawya, et al.
Publicado: (2023)

Fungal cytochrome P450 database
por: Park, Jongsun, et al.
Publicado: (2008)

Cytochrome P450 humanised mice
por: Gonzalez, Frank J
Publicado: (2004)

Intronic polymorphisms of cytochromes P450
por: Ingelman-Sundberg, Magnus, et al.
Publicado: (2010)

The Role of Cytochromes P450 in Infection
por: Stavropoulou, Elisavet, et al.
Publicado: (2018)

Cytochromes P450, Oxygen, and Evolution
por: Lewis, David F.V., et al.
Publicado: (2001)

Incidence of cardiovascular events and gastrointestinal bleeding in patients receiving clopidogrel with and without proton pump inhibitors: an updated meta-analysis
por: Cardoso, Rhanderson N, et al.
Publicado: (2015)

Use of Multimodal Therapies to Treat Severe Orthostatic Hypotension From Autonomic Failure
por: Chakrala, Teja, et al.
Publicado: (2022)

The impact of cytochrome 450 and Paraoxonase polymorphisms on clopidogrel resistance and major adverse cardiac events in coronary heart disease patients after percutaneous coronary intervention
por: Zhang, Zhaowei, et al.
Publicado: (2020)

Correlation of Cytochrome P450 Oxidoreductase Expression with the Expression of 10 Isoforms of Cytochrome P450 in Human Liver
por: Zhang, Hai-Feng, et al.
Publicado: (2016)

1-Aminobenzotriazole: A Mechanism-Based Cytochrome P450 Inhibitor and Probe of Cytochrome P450 Biology
por: de Montellano, Paul R Ortiz
Publicado: (2018)

Allosteric modulation of cytochrome P450 enzymes by the NADPH cytochrome P450 reductase FMN-containing domain
por: Burris-Hiday, Sarah D., et al.
Publicado: (2023)

Predictors of contrast induced nephropathy and the applicability of the Mehran risk score in high risk patients undergoing coronary angioplasty—A study from a tertiary care center in South India
por: Valappil, Sanjai Pattu, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_pphnl7vi4gmmf19k8fplsu5rk3