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Update Breast Cancer 2022 Part 5 – Early Stage Breast Cancer
The treatment of patients with early stage breast cancer has changed in recent years due to the introduction of pembrolizumab, olaparib, and abemaciclib. These and other drugs with the same class of active ingredient are currently in trial for various indications. This review article summarizes the...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Georg Thieme Verlag KG
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998178/ https://www.ncbi.nlm.nih.gov/pubmed/36908285 http://dx.doi.org/10.1055/a-2018-9053 |
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| author | Fehm, Tanja N. Welslau, Manfred Müller, Volkmar Lüftner, Diana Schütz, Florian Fasching, Peter A. Janni, Wolfgang Thomssen, Christoph Witzel, Isabell Beierlein, Milena Belleville, Erik Untch, Michael Thill, Marc Tesch, Hans Ditsch, Nina Lux, Michael P. Aktas, Bahriye Banys-Paluchowski, Maggie Kolberg-Liedtke, Cornelia Hartkopf, Andreas D. Wöckel, Achim Kolberg, Hans-Christian Harbeck, Nadia Stickeler, Elmar |
| author_facet | Fehm, Tanja N. Welslau, Manfred Müller, Volkmar Lüftner, Diana Schütz, Florian Fasching, Peter A. Janni, Wolfgang Thomssen, Christoph Witzel, Isabell Beierlein, Milena Belleville, Erik Untch, Michael Thill, Marc Tesch, Hans Ditsch, Nina Lux, Michael P. Aktas, Bahriye Banys-Paluchowski, Maggie Kolberg-Liedtke, Cornelia Hartkopf, Andreas D. Wöckel, Achim Kolberg, Hans-Christian Harbeck, Nadia Stickeler, Elmar |
| author_sort | Fehm, Tanja N. |
| collection | PubMed |
| description | The treatment of patients with early stage breast cancer has changed in recent years due to the introduction of pembrolizumab, olaparib, and abemaciclib. These and other drugs with the same class of active ingredient are currently in trial for various indications. This review article summarizes the latest results that have either been presented at major conferences such as the ESMO 2022 or published recently in international journals. This includes reports on newly discovered breast cancer genes, atezolizumab in neoadjuvant therapy in HER2-positive patients, long-term data from the APHINITY study, and on how preoperative peritumoral application of local anesthetics can influence the prognosis. We also present solid data on dynamic Ki-67 from the ADAPT studies. |
| format | Online Article Text |
| id | pubmed-9998178 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | Georg Thieme Verlag KG |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-99981782023-03-10 Update Breast Cancer 2022 Part 5 – Early Stage Breast Cancer Fehm, Tanja N. Welslau, Manfred Müller, Volkmar Lüftner, Diana Schütz, Florian Fasching, Peter A. Janni, Wolfgang Thomssen, Christoph Witzel, Isabell Beierlein, Milena Belleville, Erik Untch, Michael Thill, Marc Tesch, Hans Ditsch, Nina Lux, Michael P. Aktas, Bahriye Banys-Paluchowski, Maggie Kolberg-Liedtke, Cornelia Hartkopf, Andreas D. Wöckel, Achim Kolberg, Hans-Christian Harbeck, Nadia Stickeler, Elmar Geburtshilfe Frauenheilkd The treatment of patients with early stage breast cancer has changed in recent years due to the introduction of pembrolizumab, olaparib, and abemaciclib. These and other drugs with the same class of active ingredient are currently in trial for various indications. This review article summarizes the latest results that have either been presented at major conferences such as the ESMO 2022 or published recently in international journals. This includes reports on newly discovered breast cancer genes, atezolizumab in neoadjuvant therapy in HER2-positive patients, long-term data from the APHINITY study, and on how preoperative peritumoral application of local anesthetics can influence the prognosis. We also present solid data on dynamic Ki-67 from the ADAPT studies. Georg Thieme Verlag KG 2023-03-09 /pmc/articles/PMC9998178/ /pubmed/36908285 http://dx.doi.org/10.1055/a-2018-9053 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited. |
| spellingShingle | Fehm, Tanja N. Welslau, Manfred Müller, Volkmar Lüftner, Diana Schütz, Florian Fasching, Peter A. Janni, Wolfgang Thomssen, Christoph Witzel, Isabell Beierlein, Milena Belleville, Erik Untch, Michael Thill, Marc Tesch, Hans Ditsch, Nina Lux, Michael P. Aktas, Bahriye Banys-Paluchowski, Maggie Kolberg-Liedtke, Cornelia Hartkopf, Andreas D. Wöckel, Achim Kolberg, Hans-Christian Harbeck, Nadia Stickeler, Elmar Update Breast Cancer 2022 Part 5 – Early Stage Breast Cancer |
| title | Update Breast Cancer 2022 Part 5 – Early Stage Breast Cancer |
| title_full | Update Breast Cancer 2022 Part 5 – Early Stage Breast Cancer |
| title_fullStr | Update Breast Cancer 2022 Part 5 – Early Stage Breast Cancer |
| title_full_unstemmed | Update Breast Cancer 2022 Part 5 – Early Stage Breast Cancer |
| title_short | Update Breast Cancer 2022 Part 5 – Early Stage Breast Cancer |
| title_sort | update breast cancer 2022 part 5 – early stage breast cancer |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998178/ https://www.ncbi.nlm.nih.gov/pubmed/36908285 http://dx.doi.org/10.1055/a-2018-9053 |
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