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The Attenuation Mechanism and Live Vaccine Potential of a Low-Virulence Edwardsiella ictaluri Strain Obtained by Rifampicin Passaging Culture

The rifampicin-resistant strain E9-302 of Edwardsiella ictaluri strain 669 (WT) was generated by continuous passage on BHI agar plates containing increasing concentrations of rifampicin. E9-302 was attenuated significantly by 119 times to zebrafish Danio rerio compared to WT in terms of the 50% leth...

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Detalles Bibliográficos
Autores principales:	Wang, Shuyi, Hao, Jingwen, Yang, Jicheng, Zhang, Qianqian, Li, Aihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society for Microbiology and Biotechnology 2023
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998210/ https://www.ncbi.nlm.nih.gov/pubmed/36734130 http://dx.doi.org/10.4014/jmb.2210.10013

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