Influence of age, gender, previous SARS-CoV-2 infection, and pre-existing diseases in antibody response after COVID-19 vaccination: A review

Vaccines induce specific long-term immunological memory against pathogens, preventing the worsening of diseases. The COVID-19 health emergency has caused more than 6 million deaths and started a race for vaccine development. Antibody response to COVID-19 vaccines has been investigated primarily in h...

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Detalles Bibliográficos
Autores principales: Fernandes, Maria da Conceição Rodrigues, Vasconcelos, Germana Silva, de Melo, Amanda Campelo Lima, Matsui, Tamires Cardoso, Caetano, Ludmilla Freire, de Carvalho Araújo, Fernanda Montenegro, Fonseca, Marcela Helena Gambim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998295/
https://www.ncbi.nlm.nih.gov/pubmed/36921489
http://dx.doi.org/10.1016/j.molimm.2023.03.007
Descripción
Sumario:Vaccines induce specific long-term immunological memory against pathogens, preventing the worsening of diseases. The COVID-19 health emergency has caused more than 6 million deaths and started a race for vaccine development. Antibody response to COVID-19 vaccines has been investigated primarily in healthcare workers. The heterogeneity of immune responses and the behavior of this response in particular groups were still very little explored. In this review, we discuss whether antibody responses after vaccination are influenced by age, gender, previous SARS-CoV-2 infection, or pre-existing diseases.

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