Ovatodiolide inhibits SARS-CoV-2 replication and ameliorates pulmonary fibrosis through suppression of the TGF-β/TβRs signaling pathway

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection continues to pose threats to public health. The clinical manifestations of lung pathology in COVID-19 patients include sustained inflammation and pulmonary fibrosis. The macrocyclic diterpenoid ovatodiolide (OVA) has been reporte...

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Detalles Bibliográficos
Autores principales: Chiou, Wei-Chung, Huang, Guan-Jhong, Chang, Tein-Yao, Hsia, Tzu-Lan, Yu, Hao-You, Lo, Jir-Mehng, Fu, Pin-Kuei, Huang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Masson SAS. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998303/
https://www.ncbi.nlm.nih.gov/pubmed/36906971
http://dx.doi.org/10.1016/j.biopha.2023.114481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998303/
https://www.ncbi.nlm.nih.gov/pubmed/36906971
http://dx.doi.org/10.1016/j.biopha.2023.114481

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