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Brunner Gland Hamartomas—Uncommon Presentations and Endoscopic Management

Brunner gland hamartoma (BGH) is a rare condition that requires a high clinical suspicion to diagnose. Large hamartomas may initially present with iron deficiency anemia (IDA) or symptoms suggesting intestinal obstruction. Barium swallow may demonstrate the lesion, but endoscopic evaluation is the a...

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Autores principales: Khalifa, Ali, Wu, Yi-Chia, Velpari, Sugirdhana, Korman, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998406/
https://www.ncbi.nlm.nih.gov/pubmed/36891571
http://dx.doi.org/10.1177/23247096231159811
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author Khalifa, Ali
Wu, Yi-Chia
Velpari, Sugirdhana
Korman, Andrew
author_facet Khalifa, Ali
Wu, Yi-Chia
Velpari, Sugirdhana
Korman, Andrew
author_sort Khalifa, Ali
collection PubMed
description Brunner gland hamartoma (BGH) is a rare condition that requires a high clinical suspicion to diagnose. Large hamartomas may initially present with iron deficiency anemia (IDA) or symptoms suggesting intestinal obstruction. Barium swallow may demonstrate the lesion, but endoscopic evaluation is the acceptable first line management unless a concern for underlying malignancy. The present case report and literature review highlight the uncommon presentations and endoscopic role in large BGHs management. Internists should consider BGH in their differential, especially in patient with occult bleeding, IDA, or obstruction, which can be treated with endoscopic resection of large sized tumors by trained experts.
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spelling pubmed-99984062023-03-11 Brunner Gland Hamartomas—Uncommon Presentations and Endoscopic Management Khalifa, Ali Wu, Yi-Chia Velpari, Sugirdhana Korman, Andrew J Investig Med High Impact Case Rep Case Report Brunner gland hamartoma (BGH) is a rare condition that requires a high clinical suspicion to diagnose. Large hamartomas may initially present with iron deficiency anemia (IDA) or symptoms suggesting intestinal obstruction. Barium swallow may demonstrate the lesion, but endoscopic evaluation is the acceptable first line management unless a concern for underlying malignancy. The present case report and literature review highlight the uncommon presentations and endoscopic role in large BGHs management. Internists should consider BGH in their differential, especially in patient with occult bleeding, IDA, or obstruction, which can be treated with endoscopic resection of large sized tumors by trained experts. SAGE Publications 2023-03-08 /pmc/articles/PMC9998406/ /pubmed/36891571 http://dx.doi.org/10.1177/23247096231159811 Text en © 2023 American Federation for Medical Research https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Khalifa, Ali
Wu, Yi-Chia
Velpari, Sugirdhana
Korman, Andrew
Brunner Gland Hamartomas—Uncommon Presentations and Endoscopic Management
title Brunner Gland Hamartomas—Uncommon Presentations and Endoscopic Management
title_full Brunner Gland Hamartomas—Uncommon Presentations and Endoscopic Management
title_fullStr Brunner Gland Hamartomas—Uncommon Presentations and Endoscopic Management
title_full_unstemmed Brunner Gland Hamartomas—Uncommon Presentations and Endoscopic Management
title_short Brunner Gland Hamartomas—Uncommon Presentations and Endoscopic Management
title_sort brunner gland hamartomas—uncommon presentations and endoscopic management
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998406/
https://www.ncbi.nlm.nih.gov/pubmed/36891571
http://dx.doi.org/10.1177/23247096231159811
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