Casein Kinase 2 Mediates HIV- and Opioid-Induced Pathologic Phosphorylation of TAR DNA Binding Protein 43 in the Basal Ganglia

Aberrant phosphorylation and subsequent aggregation of the trans-activation response (TAR) element DNA binding protein 43 (TDP-43) is a common feature of multiple neurodegenerative disorders and contributes to disease severity. Here, we investigated whether pathologic phosphorylation of TDP-43 (pTDP...

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Detalles Bibliográficos
Autores principales: Ohene-Nyako, Michael, Nass, Sara R., Richard, Hope T., Lukande, Robert, Nicol, Melanie R., McRae, MaryPeace, Knapp, Pamela E., Hauser, Kurt F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998424/
https://www.ncbi.nlm.nih.gov/pubmed/36890725
http://dx.doi.org/10.1177/17590914231158218

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