Inhibition of NHE1 transport activity and gene transcription in DRG neurons in oxaliplatin-induced painful peripheral neurotoxicity

Oxaliplatin (OHP)-induced peripheral neurotoxicity (OIPN), one of the major dose-limiting side effects of colorectal cancer treatment, is characterized by both acute and chronic syndromes. Acute exposure to low dose OHP on dorsal root ganglion (DRG) neurons is able to induce an increase in intracell...

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Detalles Bibliográficos
Autores principales: Dionisi, Marianna, Riva, Beatrice, Delconti, Marta, Meregalli, Cristina, Chiorazzi, Alessia, Canta, Annalisa, Alberti, Paola, Carozzi, Valentina, Pozzi, Eleonora, Lim, Dmtry, Genazzani, Armando A., Distasi, Carla, Cavaletti, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998445/
https://www.ncbi.nlm.nih.gov/pubmed/36894669
http://dx.doi.org/10.1038/s41598-023-31095-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998445/
https://www.ncbi.nlm.nih.gov/pubmed/36894669
http://dx.doi.org/10.1038/s41598-023-31095-9

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