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Lantern-shaped flexible RNA origami for Smad4 mRNA delivery and growth suppression of colorectal cancer

mRNA delivery has shown high application value in the treatment of various diseases, but its effective delivery is still a major challenge at present. Herein, we propose a lantern-shaped flexible RNA origami for mRNA delivery. The origami is composed of a target mRNA scaffold and only two customized...

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Detalles Bibliográficos
Autores principales: Hu, Muren, Feng, Chang, Yuan, Qianqin, Liu, Chenbin, Ge, Bujun, Sun, Fenyong, Zhu, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998469/
https://www.ncbi.nlm.nih.gov/pubmed/36894556
http://dx.doi.org/10.1038/s41467-023-37020-y