Cargando…

TCF7L1 Accelerates Smooth Muscle Cell Phenotypic Switching and Aggravates Abdominal Aortic Aneurysms

Phenotypic switching of vascular smooth muscle cells is a central process in abdominal aortic aneurysm (AAA) pathology. We found that knockdown TCF7L1 (transcription factor 7-like 1), a member of the TCF/LEF (T cell factor/lymphoid enhancer factor) family of transcription factors, inhibits vascular...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jing, Tian, Xiaoxiang, Yan, Chenghui, Wu, Hanlin, Bu, Yuxin, Li, Jia, Liu, Dan, Han, Yaling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Research - Preclinical
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998605/ https://www.ncbi.nlm.nih.gov/pubmed/36908661 http://dx.doi.org/10.1016/j.jacbts.2022.07.012

Ejemplares similares

TCF7L1 Exacerbates Abdominal Aortic Aneurysm Prevalence and Severity
por: Khachigian, Levon M., et al.
Publicado: (2023)

PRDM16 deficiency in vascular smooth muscle cells aggravates abdominal aortic aneurysm
por: Wang, Zhenguo, et al.
Publicado: (2023)

TRPV1 inhibits smooth muscle cell phenotype switching in a mouse model of abdominal aortic aneurysm
por: Wang, Shuo, et al.
Publicado: (2020)

Propionate Alleviates Abdominal Aortic Aneurysm by Modulating Colonic Regulatory T-Cell Expansion and Recirculation
por: Yang, Fen, et al.
Publicado: (2022)

Trimethylamine N-Oxide Promotes Abdominal Aortic Aneurysm Formation by Aggravating Aortic Smooth Muscle Cell Senescence in Mice
por: Hu, Jiaxin, et al.
Publicado: (2022)

Genetic Deletion of Socs3 in Smooth Muscle Cells Ameliorates Aortic Dissection in Mice
por: Hirakata, Saki, et al.
Publicado: (2020)

Sildenafil (Viagra) Aggravates the Development of Experimental Abdominal Aortic Aneurysm
por: Zhang, Chongyang, et al.
Publicado: (2022)

IgE Aggravates the Senescence of Smooth Muscle Cells in Abdominal Aortic Aneurysm by Upregulating LincRNA-p21
por: Guo, Wenjun, et al.
Publicado: (2019)

Exploring smooth muscle phenotype and function in a bioreactor model of abdominal aortic aneurysm
por: Riches, Kirsten, et al.
Publicado: (2013)

From Colon to Aortic Aneurysm: Trek of the Treg
por: Freedman, Neil J.
Publicado: (2022)

Dissecting Abdominal Aortic Aneurysm Is Aggravated by Genetic Inactivation of LIGHT (TNFSF14)
por: Herrero-Cervera, Andrea, et al.
Publicado: (2021)

Genetic and Epigenetic Mechanisms Underlying Vascular Smooth Muscle Cell Phenotypic Modulation in Abdominal Aortic Aneurysm
por: Gurung, Rijan, et al.
Publicado: (2020)

Single-cell RNA sequencing reveals the vascular smooth muscle cell phenotypic landscape in aortic aneurysm
por: Cao, Genmao, et al.
Publicado: (2023)

Protective Role for Smooth Muscle Cell Hepcidin in Abdominal Aortic Aneurysm
por: Loick, Paul, et al.
Publicado: (2023)

Attenuation of Smooth Muscle Cell Phenotypic Switching by Angiotensin 1-7 Protects against Thoracic Aortic Aneurysm
por: Jadli, Anshul S., et al.
Publicado: (2022)

The Role and Mechanism of SIRT6 in Regulating Phenotype Transformation of Vascular Smooth Muscle Cells in Abdominal Aortic Aneurysm
por: Guan, Xiaomei, et al.
Publicado: (2022)

CREG ameliorates the phenotypic switching of cardiac fibroblasts after myocardial infarction via modulation of CDC42
por: Liu, Dan, et al.
Publicado: (2021)

Coexistence of expanding abdominal aortic aneurysm and aggravated intervertebral disc extrusion -a case report-
por: Kim, Nan Seol, et al.
Publicado: (2013)

Induction of ferroptosis promotes vascular smooth muscle cell phenotypic switching and aggravates neointimal hyperplasia in mice
por: Zhang, Shunchi, et al.
Publicado: (2022)

Abdominal Aortic Aneurysm Formation with a Focus on Vascular Smooth Muscle Cells
por: Qian, Guoqing, et al.
Publicado: (2022)

Aggravated Atherosclerosis and Vascular Inflammation With Reduced Kidney Function Depend on Interleukin-17 Receptor A and Are Normalized by Inhibition of Interleukin-17A
por: Nordlohne, Johannes, et al.
Publicado: (2018)

VPO1 Modulates Vascular Smooth Muscle Cell Phenotypic Switch by Activating Extracellular Signal‐regulated Kinase 1/2 (ERK 1/2) in Abdominal Aortic Aneurysms
por: Peng, Huihui, et al.
Publicado: (2018)

MicroRNA‐199a‐5p aggravates angiotensin II–induced vascular smooth muscle cell senescence by targeting Sirtuin‐1 in abdominal aortic aneurysm
por: Tao, Wuyuan, et al.
Publicado: (2021)

HDAC6 Regulates the MRTF-A/SRF Axis and Vascular Smooth Muscle Cell Plasticity
por: Zhang, Mengxue, et al.
Publicado: (2018)

Defective autophagy in vascular smooth muscle cells enhances the healing of abdominal aortic aneurysm
por: Mochida, Akihiro, et al.
Publicado: (2021)

6-Month Evaluation of a Transcatheter Aortic Valve (Myval) in a Novel Ovine, Supra-Aortic Banding Model
por: Buszman, Piotr P., et al.
Publicado: (2022)

General Considerations of Ruptured Abdominal Aortic Aneurysm: Ruptured Abdominal Aortic Aneurysm
por: Lee, Chung Won, et al.
Publicado: (2015)

Ruptured Abdominal Aortic Aneurysm with Antecedent Endovascular Repair of Abdominal Aortic Aneurysm
por: Cho, Jae S.
Publicado: (2014)

Phenotypic and Functional Changes of Endothelial and Smooth Muscle Cells in Thoracic Aortic Aneurysms
por: Malashicheva, Anna, et al.
Publicado: (2016)

CircRNA Chordc1 protects mice from abdominal aortic aneurysm by contributing to the phenotype and growth of vascular smooth muscle cells
por: He, Xiang, et al.
Publicado: (2021)

Impaired smooth muscle cell contractility as a novel concept of abdominal aortic aneurysm pathophysiology
por: Bogunovic, Natalija, et al.
Publicado: (2019)

Micromanaging Abdominal Aortic Aneurysms
por: Maegdefessel, Lars, et al.
Publicado: (2013)

Giant abdominal aortic aneurysms
por: Ng, Joshua I., et al.
Publicado: (2021)

Mechanosignals in abdominal aortic aneurysms
por: Lowis, Christiana, et al.
Publicado: (2023)

DCBL2 Deficiency Contributes to Aortic Stenosis via Increased BMP2 Signaling
por: Armstrong, David W.J., et al.
Publicado: (2022)

Adipose Stem Cells Promote Smooth Muscle Cells to Secrete Elastin in Rat Abdominal Aortic Aneurysm
por: Tian, Xiaohong, et al.
Publicado: (2014)

Excessive EP4 Signaling in Smooth Muscle Cells Induces Abdominal Aortic Aneurysm by Amplifying Inflammation
por: Hiromi, Taro, et al.
Publicado: (2020)

Preservation of Smooth Muscle Cell Integrity and Function: A Target for Limiting Abdominal Aortic Aneurysm Expansion?
por: Clark, Emily R., et al.
Publicado: (2022)

Inhibition of smooth muscle cell death by Angiotensin 1-7 protects against abdominal aortic aneurysm
por: Jadli, Anshul S., et al.
Publicado: (2023)

Phenotypic characterisation of breast cancer: the role of CDC42
por: Chrysanthou, Eleni, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_gaudokldglh7lopagl4tl4rujd