Gut microbiota alters host bile acid metabolism to contribute to intrahepatic cholestasis of pregnancy

Intrahepatic cholestasis of pregnancy (ICP) is a female pregnancy-specific disorder that is characterized by increased serum bile acid and adverse fetal outcomes. The aetiology and mechanism of ICP are poorly understood; thus, existing therapies have been largely empiric. Here we show that the gut m...

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Detalles Bibliográficos
Autores principales: Tang, Bo, Tang, Li, Li, Shengpeng, Liu, Shuang, He, Jialin, Li, Pan, Wang, Sumin, Yang, Min, Zhang, Longhui, Lei, Yuanyuan, Tu, Dianji, Tang, Xuefeng, Hu, Hua, Ouyang, Qin, Chen, Xia, Yang, Shiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998625/
https://www.ncbi.nlm.nih.gov/pubmed/36894566
http://dx.doi.org/10.1038/s41467-023-36981-4

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