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Novel method of differentiating human induced pluripotent stem cells to mature cardiomyocytes via Sfrp2

Current methods to generate cardiomyocytes from induced pluripotent stem cells (iPSc) utilize broad-spectrum pharmacological inhibitors. These methods give rise to cardiomyocytes which are typically immature. Since we have recently demonstrated that cardiomyogenesis in vitro and in vivo requires Sfr...

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Detalles Bibliográficos
Autores principales:	Hsueh, Ying-Chang, Pratt, Richard E., Dzau, Victor J., Hodgkinson, Conrad P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998650/ https://www.ncbi.nlm.nih.gov/pubmed/36894665 http://dx.doi.org/10.1038/s41598-023-31144-3

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