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Transfer of passive immunity and survival in Jersey heifer calves fed heat-treated pooled colostrum

Acquisition of adequate transfer of passive immunity (ATPI) by calves depends on the absorption of sufficient mass of colostral immunoglobulin G (IgG). Several studies report conflicting evidence regarding the ability of feeding pooled colostrum to achieve ATPI. Pooling colostrum is practical and ef...

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Autores principales: Bandlow, Katherine S., King, Ailbhe, Kennicutt, Kelsie C., Brody, Shoshana, Chigerwe, Munashe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998901/
https://www.ncbi.nlm.nih.gov/pubmed/36908520
http://dx.doi.org/10.3389/fvets.2023.1094272
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author Bandlow, Katherine S.
King, Ailbhe
Kennicutt, Kelsie C.
Brody, Shoshana
Chigerwe, Munashe
author_facet Bandlow, Katherine S.
King, Ailbhe
Kennicutt, Kelsie C.
Brody, Shoshana
Chigerwe, Munashe
author_sort Bandlow, Katherine S.
collection PubMed
description Acquisition of adequate transfer of passive immunity (ATPI) by calves depends on the absorption of sufficient mass of colostral immunoglobulin G (IgG). Several studies report conflicting evidence regarding the ability of feeding pooled colostrum to achieve ATPI. Pooling colostrum is practical and efficient for some dairies, and recommendations are required to prevent failure of transfer of passive immunity (FTPI) in calves following pooling. This study aimed to determine the effect of pooling colostrum on serum IgG concentrations, FTPI, and preweaning mortality in calves. A prospective study was performed on two conventional Jersey dairy farms where heat treatment of colostrum occurred in the same colostrum processing kitchen. Four to 10 cows contributed to colostrum pools. A sample of the colostrum pool fed to the calves and serum from calves at 24–72 h was collected for IgG concentration determination by single radial immunodiffusion assay. Multivariable and logistic regression analyses were performed to evaluate factors that predicated serum IgG concentrations and the probability of FTPI, respectively. A Cox proportional hazard model analysis was performed to determine risk factors for mortality over the preweaning period. A total of 164 calves fed 28 colostrum pools were enrolled. Birth weight, number of colostrum feedings and pool IgG concentrations were significant predictors of calf serum IgG concentrations at 24–72 h, whereas the number of colostrum feedings and age at bleeding to determine passive transfer status were not significant predictors of calf serum IgG concentrations at 24–72 h. The prevalence of FTPI was 4.9%. Birth weight, pool IgG concentrations, number of colostrum feedings, and age at bleeding to check for passive transfer status were not significant predictors of the probability of FTPI at 24–72 h. The incidence of mortality was 4.3%. Passive transfer status was not a predictor of mortality. Our study demonstrates the effect of pooling colostrum on serum IgG concentrations even in herds where colostrum with higher median colostrum IgG concentrations is fed to calves. The results emphasize the recommendations to assess pooled colostrum IgG concentrations before feeding calves.
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spelling pubmed-99989012023-03-11 Transfer of passive immunity and survival in Jersey heifer calves fed heat-treated pooled colostrum Bandlow, Katherine S. King, Ailbhe Kennicutt, Kelsie C. Brody, Shoshana Chigerwe, Munashe Front Vet Sci Veterinary Science Acquisition of adequate transfer of passive immunity (ATPI) by calves depends on the absorption of sufficient mass of colostral immunoglobulin G (IgG). Several studies report conflicting evidence regarding the ability of feeding pooled colostrum to achieve ATPI. Pooling colostrum is practical and efficient for some dairies, and recommendations are required to prevent failure of transfer of passive immunity (FTPI) in calves following pooling. This study aimed to determine the effect of pooling colostrum on serum IgG concentrations, FTPI, and preweaning mortality in calves. A prospective study was performed on two conventional Jersey dairy farms where heat treatment of colostrum occurred in the same colostrum processing kitchen. Four to 10 cows contributed to colostrum pools. A sample of the colostrum pool fed to the calves and serum from calves at 24–72 h was collected for IgG concentration determination by single radial immunodiffusion assay. Multivariable and logistic regression analyses were performed to evaluate factors that predicated serum IgG concentrations and the probability of FTPI, respectively. A Cox proportional hazard model analysis was performed to determine risk factors for mortality over the preweaning period. A total of 164 calves fed 28 colostrum pools were enrolled. Birth weight, number of colostrum feedings and pool IgG concentrations were significant predictors of calf serum IgG concentrations at 24–72 h, whereas the number of colostrum feedings and age at bleeding to determine passive transfer status were not significant predictors of calf serum IgG concentrations at 24–72 h. The prevalence of FTPI was 4.9%. Birth weight, pool IgG concentrations, number of colostrum feedings, and age at bleeding to check for passive transfer status were not significant predictors of the probability of FTPI at 24–72 h. The incidence of mortality was 4.3%. Passive transfer status was not a predictor of mortality. Our study demonstrates the effect of pooling colostrum on serum IgG concentrations even in herds where colostrum with higher median colostrum IgG concentrations is fed to calves. The results emphasize the recommendations to assess pooled colostrum IgG concentrations before feeding calves. Frontiers Media S.A. 2023-02-24 /pmc/articles/PMC9998901/ /pubmed/36908520 http://dx.doi.org/10.3389/fvets.2023.1094272 Text en Copyright © 2023 Bandlow, King, Kennicutt, Brody and Chigerwe. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Bandlow, Katherine S.
King, Ailbhe
Kennicutt, Kelsie C.
Brody, Shoshana
Chigerwe, Munashe
Transfer of passive immunity and survival in Jersey heifer calves fed heat-treated pooled colostrum
title Transfer of passive immunity and survival in Jersey heifer calves fed heat-treated pooled colostrum
title_full Transfer of passive immunity and survival in Jersey heifer calves fed heat-treated pooled colostrum
title_fullStr Transfer of passive immunity and survival in Jersey heifer calves fed heat-treated pooled colostrum
title_full_unstemmed Transfer of passive immunity and survival in Jersey heifer calves fed heat-treated pooled colostrum
title_short Transfer of passive immunity and survival in Jersey heifer calves fed heat-treated pooled colostrum
title_sort transfer of passive immunity and survival in jersey heifer calves fed heat-treated pooled colostrum
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998901/
https://www.ncbi.nlm.nih.gov/pubmed/36908520
http://dx.doi.org/10.3389/fvets.2023.1094272
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