Pleiotrophin drives a prometastatic immune niche in breast cancer

Metastatic cancer cells adapt to thrive in secondary organs. To investigate metastatic adaptation, we performed transcriptomic analysis of metastatic and non-metastatic murine breast cancer cells. We found that pleiotrophin (PTN), a neurotrophic cytokine, is a metastasis-associated factor that is ex...

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Detalles Bibliográficos
Autores principales: Ganguly, Debolina, Schmidt, Marcel O., Coleman, Morgan, Ngo, Tuong-Vi Cindy, Sorrelle, Noah, Dominguez, Adrian T.A., Murimwa, Gilbert Z., Toombs, Jason E., Lewis, Cheryl, Fang, Yisheng V., Valdes-Mora, Fatima, Gallego-Ortega, David, Wellstein, Anton, Brekken, Rolf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998964/
https://www.ncbi.nlm.nih.gov/pubmed/36828390
http://dx.doi.org/10.1084/jem.20220610

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