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Proteolytic regulation of a galectin-3/Lrp1 axis controls osteoclast-mediated bone resorption

Bone-resorbing osteoclasts mobilize proteolytic enzymes belonging to the matrix metalloproteinase (MMP) family to directly degrade type I collagen, the dominant extracellular matrix component of skeletal tissues. While searching for additional MMP substrates critical to bone resorption, Mmp9/Mmp14 d...

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Detalles Bibliográficos
Autores principales:	Zhu, Lingxin, Tang, Yi, Li, Xiao-Yan, Kerk, Samuel A., Lyssiotis, Costas A., Sun, Xiaoyue, Wang, Zijun, Cho, Jung-Sun, Ma, Jun, Weiss, Stephen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998966/ https://www.ncbi.nlm.nih.gov/pubmed/36880731 http://dx.doi.org/10.1083/jcb.202206121

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