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ABC-GOALScl score predicts admission to the intensive care unit and mortality of COVID-19 patients over 60 years of age

BACKGROUND: One of the risk factors for getting seriously ill from COVID-19 and reaching high mortality rates is older age. Older age is also associated with comorbidities, which are risk factors for severe COVID-19 infection. Among the tools that have been evaluated to predict intensive care unit (...

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Autores principales: Camacho-Moll, María Elena, Ramírez-Daher, Zayra, Escobedo-Guajardo, Brenda Leticia, Dávila-Valero, Julio César, Rodríguez-de la Garza, Brenda Ludmila, Bermúdez de León, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999052/
https://www.ncbi.nlm.nih.gov/pubmed/36899318
http://dx.doi.org/10.1186/s12877-023-03864-8
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author Camacho-Moll, María Elena
Ramírez-Daher, Zayra
Escobedo-Guajardo, Brenda Leticia
Dávila-Valero, Julio César
Rodríguez-de la Garza, Brenda Ludmila
Bermúdez de León, Mario
author_facet Camacho-Moll, María Elena
Ramírez-Daher, Zayra
Escobedo-Guajardo, Brenda Leticia
Dávila-Valero, Julio César
Rodríguez-de la Garza, Brenda Ludmila
Bermúdez de León, Mario
author_sort Camacho-Moll, María Elena
collection PubMed
description BACKGROUND: One of the risk factors for getting seriously ill from COVID-19 and reaching high mortality rates is older age. Older age is also associated with comorbidities, which are risk factors for severe COVID-19 infection. Among the tools that have been evaluated to predict intensive care unit (ICU) admission and mortality is ABC-GOALScl. AIM: In the present study we validated the utility of ABC-GOALScl to predict in-hospital mortality in subjects over 60 years of age who were positive for SARS-CoV-2 virus at the moment of admission with the purpose of optimizing sanitary resources and offering personalized treatment for these patients. METHODS: This was an observational, descriptive, transversal, non-interventional and retrospective study of subjects (≥ 60 years of age), hospitalized due to COVID-19 infection at a general hospital in northeastern Mexico. A logistical regression model was used for data analysis. RESULTS: Two hundred forty-three subjects were included in the study, whom 145 (59.7%) passed away, while 98 (40.3%) were discharged. Average age was 71, and 57.6% were male. The prediction model ABC-GOALScl included sex, body mass index, Charlson comorbidity index, dyspnea, arterial pressure, respiratory frequency, SpFi coefficient (Saturation of oxygen/Fraction of inspired oxygen ratio), serum levels of glucose, albumin, and lactate dehydrogenase; all were measured at the moment of admission. The area under the curve for the scale with respect to the variable of discharge due to death was 0.73 (IC 95% = 0.662—0.792). CONCLUSION: The ABC-GOALScl scale to predict ICU admission in COVID-19 patients is also useful to predict in-hospital death in COVID-19 patients  ≥ 60 years old.
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spelling pubmed-99990522023-03-10 ABC-GOALScl score predicts admission to the intensive care unit and mortality of COVID-19 patients over 60 years of age Camacho-Moll, María Elena Ramírez-Daher, Zayra Escobedo-Guajardo, Brenda Leticia Dávila-Valero, Julio César Rodríguez-de la Garza, Brenda Ludmila Bermúdez de León, Mario BMC Geriatr Research BACKGROUND: One of the risk factors for getting seriously ill from COVID-19 and reaching high mortality rates is older age. Older age is also associated with comorbidities, which are risk factors for severe COVID-19 infection. Among the tools that have been evaluated to predict intensive care unit (ICU) admission and mortality is ABC-GOALScl. AIM: In the present study we validated the utility of ABC-GOALScl to predict in-hospital mortality in subjects over 60 years of age who were positive for SARS-CoV-2 virus at the moment of admission with the purpose of optimizing sanitary resources and offering personalized treatment for these patients. METHODS: This was an observational, descriptive, transversal, non-interventional and retrospective study of subjects (≥ 60 years of age), hospitalized due to COVID-19 infection at a general hospital in northeastern Mexico. A logistical regression model was used for data analysis. RESULTS: Two hundred forty-three subjects were included in the study, whom 145 (59.7%) passed away, while 98 (40.3%) were discharged. Average age was 71, and 57.6% were male. The prediction model ABC-GOALScl included sex, body mass index, Charlson comorbidity index, dyspnea, arterial pressure, respiratory frequency, SpFi coefficient (Saturation of oxygen/Fraction of inspired oxygen ratio), serum levels of glucose, albumin, and lactate dehydrogenase; all were measured at the moment of admission. The area under the curve for the scale with respect to the variable of discharge due to death was 0.73 (IC 95% = 0.662—0.792). CONCLUSION: The ABC-GOALScl scale to predict ICU admission in COVID-19 patients is also useful to predict in-hospital death in COVID-19 patients  ≥ 60 years old. BioMed Central 2023-03-10 /pmc/articles/PMC9999052/ /pubmed/36899318 http://dx.doi.org/10.1186/s12877-023-03864-8 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Camacho-Moll, María Elena
Ramírez-Daher, Zayra
Escobedo-Guajardo, Brenda Leticia
Dávila-Valero, Julio César
Rodríguez-de la Garza, Brenda Ludmila
Bermúdez de León, Mario
ABC-GOALScl score predicts admission to the intensive care unit and mortality of COVID-19 patients over 60 years of age
title ABC-GOALScl score predicts admission to the intensive care unit and mortality of COVID-19 patients over 60 years of age
title_full ABC-GOALScl score predicts admission to the intensive care unit and mortality of COVID-19 patients over 60 years of age
title_fullStr ABC-GOALScl score predicts admission to the intensive care unit and mortality of COVID-19 patients over 60 years of age
title_full_unstemmed ABC-GOALScl score predicts admission to the intensive care unit and mortality of COVID-19 patients over 60 years of age
title_short ABC-GOALScl score predicts admission to the intensive care unit and mortality of COVID-19 patients over 60 years of age
title_sort abc-goalscl score predicts admission to the intensive care unit and mortality of covid-19 patients over 60 years of age
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999052/
https://www.ncbi.nlm.nih.gov/pubmed/36899318
http://dx.doi.org/10.1186/s12877-023-03864-8
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