Inhalation of an RNA aptamer that selectively binds extracellular histones protects from acute lung injury

Acute lung injury (ALI) is a syndrome of acute inflammation, barrier disruption, and hypoxemic respiratory failure associated with high morbidity and mortality. Diverse conditions lead to ALI, including inhalation of toxic substances, aspiration of gastric contents, infection, and trauma. A shared m...

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Detalles Bibliográficos
Autores principales: Lei, Beilei, Wang, Chaojian, Snow, Kamie, Graton, Murilo E., Tighe, Robert M., Fager, Ammon M., Hoffman, Maureane R., Giangrande, Paloma H., Miller, Francis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999168/
https://www.ncbi.nlm.nih.gov/pubmed/36910716
http://dx.doi.org/10.1016/j.omtn.2023.02.021

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