Targeting receptor tyrosine kinases in ovarian cancer: Genomic dysregulation, clinical evaluation of inhibitors, and potential for combinatorial therapies

Epithelial ovarian cancer (EOC) remains one of the leading causes of cancer-related deaths among women worldwide. Receptor tyrosine kinases (RTKs) have long been sought as therapeutic targets for EOC, as they are frequently hyperactivated in primary tumors and drive disease relapse, progression, and...

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Detalles Bibliográficos
Autores principales: Wei, Ying, Erfani, Sonia, Schweer, David, de Gouvea, Rafael, Qadir, Javeria, Shi, Junfeng, Cheng, Kai, Wu, Dabao, Craven, Rolf, Wu, Yadi, Olivier, Thibault, Baldwin, Lauren A., Zhou, Binhua, Zhou, Ying, Zhao, Weidong, Yang, Burton B., Ueland, Frederick R., Yang, Xiuwei H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999170/
https://www.ncbi.nlm.nih.gov/pubmed/36911068
http://dx.doi.org/10.1016/j.omto.2023.02.006

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