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Transcription factor AP-2α activates RNA polymerase III–directed transcription and tumor cell proliferation by controlling expression of c-MYC and p53

Deregulation of transcription factor AP2 alpha (TFAP2A) and RNA polymerase III (Pol III) products is associated with tumorigenesis. However, the mechanism underlying this event is not fully understood and the connection between TFAP2A and Pol III–directed transcription has not been investigated. Her...

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Detalles Bibliográficos
Autores principales: Wang, Juan, Chen, Qiyue, Peng, Feixia, Zhao, Shasha, Zhang, Cheng, Song, Xiaoye, Yu, Deen, Wu, Zhongyu, Du, Jiannan, Ni, Hongwei, Deng, Huan, Deng, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999235/
https://www.ncbi.nlm.nih.gov/pubmed/36707053
http://dx.doi.org/10.1016/j.jbc.2023.102945