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Celastrol targeting Nedd4 reduces Nrf2-mediated oxidative stress in astrocytes after ischemic stroke

Stroke is the second leading cause of death worldwide, and oxidative stress plays a crucial role. Celastrol exhibits strong antioxidant properties in several diseases; however, whether it can affect oxidation in cerebral ischemic-reperfusion injury (CIRI) remains unclear. This study aimed to determi...

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Detalles Bibliográficos
Autores principales:	Hong, Zexuan, Cao, Jun, Liu, Dandan, Liu, Maozhu, Chen, Mengyuan, Zeng, Fanning, Qin, Zaisheng, Wang, Jigang, Tao, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Xi'an Jiaotong University 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999302/ https://www.ncbi.nlm.nih.gov/pubmed/36908855 http://dx.doi.org/10.1016/j.jpha.2022.12.002

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