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Novel insights into histone lysine methyltransferases in cancer therapy: From epigenetic regulation to selective drugs

The reversible and precise temporal and spatial regulation of histone lysine methyltransferases (KMTs) is essential for epigenome homeostasis. The dysregulation of KMTs is associated with tumor initiation, metastasis, chemoresistance, invasiveness, and the immune microenvironment. Therapeutically, t...

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Detalles Bibliográficos
Autores principales: Liao, Qili, Yang, Jie, Ge, Shengfang, Chai, Peiwei, Fan, Jiayan, Jia, Renbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999304/
https://www.ncbi.nlm.nih.gov/pubmed/36908859
http://dx.doi.org/10.1016/j.jpha.2022.11.009