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Development and validation of an UPLC-ESI-MS/MS method for quantification of duvelisib in plasma: application to pharmacokinetic study in rats

Duvelisib (DUV) is a new oral phosphoinositide-3-kinase (PI3K)-δ and PI3K-γ inhibitor. It is used for the treatment of relapsed or refractory chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). This study describes the development and validation of a new highly sensitive and eff...

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Detalles Bibliográficos
Autores principales:	Darwish, Ibrahim A., Alzoman, Nourah Z., Almomen, Aliyah, Almehizia, Abdulrahman A., Attwa, Mohamed W., Darwish, Hany W., Sayed, Ahmed Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999367/ https://www.ncbi.nlm.nih.gov/pubmed/36909770 http://dx.doi.org/10.1039/d3ra00310h

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