Cargando…

Immunohistochemical analysis of expression of VEGFR2, KIT, PDGFR-β, and CDK4 in canine urothelial carcinoma

Urothelial carcinomas (UCs), also known as transitional cell carcinomas, are the most common canine urinary tract neoplasms. Tyrosine kinases (TKs) are enzymes that tightly regulate cell growth and differentiation through phosphorylation. Receptor TK (RTK) inhibitors are currently used to treat UCs....

Descripción completa

Detalles Bibliográficos
Autores principales:	Setyo, Laura C., Donahoe, Shannon L., Shearer, Patrick L., Wang, Penghao, Krockenberger, Mark B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2023
Materias:	Full Scientific Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999406/ https://www.ncbi.nlm.nih.gov/pubmed/36648148 http://dx.doi.org/10.1177/10406387221146247

Ejemplares similares

KIT Somatic Mutations and Immunohistochemical Expression in Canine Oral Melanoma
por: Brocca, Ginevra, et al.
Publicado: (2020)

Expression and prognostic value of VEGFR-2, PDGFR-β, and c-Met in advanced hepatocellular carcinoma
por: Chu, Jie Sheng, et al.
Publicado: (2013)

PDGFRα/β and VEGFR2 polymorphisms in colorectal cancer: incidence and implications in clinical outcome
por: Estevez-Garcia, Purificacion, et al.
Publicado: (2012)

Immunohistochemical Expression of Platelet-Derived Growth Factor Receptor β (PDGFR-β) in Canine Cutaneous Peripheral Nerve Sheath Tumors: A Preliminary Study
por: Aluai-Cunha, Catarina, et al.
Publicado: (2022)

Effect of VEGFR, PDGFR and PI3K/mTOR Targeting in Glioblastoma
por: PURCARU, S.O., et al.
Publicado: (2015)

Immunohistochemical expression of CD117/KIT, HER2, and Erβ in schistosomal and non-schistosomal urothelial carcinoma of Egyptian patients
por: Khalifa, Sara E.
Publicado: (2023)

Deregulation of VEGFR-2 and PDGFR Expression and Microvascular Density in a Triple-Negative Model of Canine Malignant Mammary Tumors with Lymph Node or Lung Metastasis
por: dos Anjos, Denner Santos, et al.
Publicado: (2019)

Fulminant Tritrichomonas foetus ‘feline genotype’ infection in a 3-month old kitten associated with viral co-infection
por: Setyo, Laura, et al.
Publicado: (2019)

VEGFR2(+)PDGFRβ(+) circulating precursor cells participate in capillary restoration after hyperoxia acute lung injury (HALI)
por: Jones, Rosemary, et al.
Publicado: (2009)

The VEGFR/PDGFR tyrosine kinase inhibitor, ABT-869, blocks necroptosis by targeting RIPK1 kinase
por: Pierotti, Catia L., et al.
Publicado: (2023)

Molecular Characterization of PDGFR-α/PDGF-A and c-KIT/SCF in Gliosarcomas
por: Reis, Rui M., et al.
Publicado: (2005)

PDGFR‐β and kidney fibrosis
por: Ortiz, Alberto
Publicado: (2020)

The Three Receptor Tyrosine Kinases c-KIT, VEGFR2 and PDGFRα, Closely Spaced at 4q12, Show Increased Protein Expression in Triple-Negative Breast Cancer
por: Jansson, Sara, et al.
Publicado: (2014)

Transactivation of PDGFRβ by dopamine D4 receptor does not require PDGFRβ dimerization
por: Chi, Sum Shing, et al.
Publicado: (2010)

Quantification of normetanephrine in canine urine using ELISA: evaluation of factors affecting results
por: Höglund, Katja, et al.
Publicado: (2021)

Flumatinib, a selective inhibitor of BCR-ABL/PDGFR/KIT, effectively overcomes drug resistance of certain KIT mutants
por: Zhao, Jie, et al.
Publicado: (2014)

PDGFRβ(+)/c-kit(+) pulp cells are odontoblastic progenitors capable of producing dentin-like structure in vitro and in vivo
por: Cai, Shiwei, et al.
Publicado: (2016)

A review of neosporosis and pathologic findings of Neospora caninum infection in wildlife
por: Donahoe, Shannon L., et al.
Publicado: (2015)

A saliva urea test strip for use in feline and canine patients: a pilot study
por: Nickel, Matthew R., et al.
Publicado: (2022)

PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα
por: Fantauzzo, Katherine A., et al.
Publicado: (2016)

Impact of VEGF, VEGFR, PDGFR, HIF and ERCC1 gene polymorphisms on thymic malignancies outcome after thymectomy
por: Berardi, Rossana, et al.
Publicado: (2015)

Small Molecular-Sized Artesunate Attenuates Ocular Neovascularization via VEGFR2, PKCα, and PDGFR Targets
por: Zong, Yao, et al.
Publicado: (2016)

Structural optimization and evaluation of novel 2-pyrrolidone-fused (2-oxoindolin-3-ylidene)methylpyrrole derivatives as potential VEGFR-2/PDGFRβ inhibitors
por: Yang, Ting-Hsuan, et al.
Publicado: (2017)

The usefulness of c-Kit in the immunohistochemical assessment of melanocytic lesions
por: Pilloni, L., et al.
Publicado: (2011)

Next generation sequencing analysis of platinum refractory advanced germ cell tumor sensitive to Sunitinib (Sutent®) a VEGFR2/PDGFRβ/c-kit/ FLT3/RET/CSF1R inhibitor in a phase II trial
por: Subbiah, Vivek, et al.
Publicado: (2014)

Landscape of Targeted Anti-Cancer Drug Synergies in Melanoma Identifies a Novel BRAF-VEGFR/PDGFR Combination Treatment
por: Friedman, Adam A., et al.
Publicado: (2015)

VEGF-A/VEGFR-2 and FGF-2/FGFR-1 but not PDGF-BB/PDGFR-β play important roles in promoting immature and inflammatory intraplaque angiogenesis
por: Mao, Yang, et al.
Publicado: (2018)

Total observed error, total allowable error, and QC rules for canine serum and urine cortisol achievable with the Immulite 2000 Xpi cortisol immunoassay
por: Korchia, Jeremie, et al.
Publicado: (2022)

Evaluation of canine and feline leukocyte differential counts obtained with the scil vCell 5 compared to the Advia 2120 hematology analyzer and a manual method
por: Zelmer, Kim-Lina Charlotte, et al.
Publicado: (2023)

Molecular Modeling Study of c-KIT/PDGFRα Dual Inhibitors for the Treatment of Gastrointestinal Stromal Tumors
por: Keretsu, Seketoulie, et al.
Publicado: (2020)

Phase Ib study of CP-868,596, a PDGFR inhibitor, combined with docetaxel with or without axitinib, a VEGFR inhibitor
por: Michael, M, et al.
Publicado: (2010)

The Activation of PDGFRβ on Mononuclear Stromal/Tumor Cells in Giant Cell Tumor of Bone After Denosumab Treatment. An Immunohistochemical Study of Five Cases
por: Antal, Imre, et al.
Publicado: (2022)

ARF sees Pdgfrβ through the miR
por: Reed, Sara M, et al.
Publicado: (2014)

Dysregulated mesenchymal PDGFR‐β drives kidney fibrosis
por: Buhl, Eva M, et al.
Publicado: (2020)

KRAS, EGFR, PDGFR-α, KIT and COX-2 status in carcinoma showing thymus-like elements (CASTLE)
por: Veits, Lothar, et al.
Publicado: (2014)

Platelet Derived Growth Factor Alpha (PDGFRα) Induces the Activation of Cardiac Fibroblasts by Activating c-Kit
por: Wang, Lexun, et al.
Publicado: (2017)

Immunohistochemical localization of VEGFR-2 in mouse mammary gland during reproductive cycle
por: Islam, Mohammad Saiful, et al.
Publicado: (2021)

M2 Macrophages Promote PDGFRβ(+) Pericytes Migration After Spinal Cord Injury in Mice via PDGFB/PDGFRβ Pathway
por: Li, Ziyu, et al.
Publicado: (2021)

Increased PDGFR-beta and VEGFR-2 protein levels are associated with resistance to platinum-based chemotherapy and adverse outcome of ovarian cancer patients
por: Avril, Stefanie, et al.
Publicado: (2017)

Immunohistochemical study of doublecortin and nucleostemin in canine brain
por: De Nevi, E., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_f7se2ohavndhn2sqmtadqgf9n7