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Directed Biosynthesis of Mitragynine Stereoisomers

[Image: see text] Mitragyna speciosa (“kratom”) is used as a natural remedy for pain and management of opioid dependence. The pharmacological properties of kratom have been linked to a complex mixture of monoterpene indole alkaloids, most notably mitragynine. Here, we report the central biosynthetic...

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Detalles Bibliográficos
Autores principales: Schotte, Carsten, Jiang, Yindi, Grzech, Dagny, Dang, Thu-Thuy T., Laforest, Larissa C., León, Francisco, Mottinelli, Marco, Nadakuduti, Satya Swathi, McCurdy, Christopher R., O’Connor, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999412/
https://www.ncbi.nlm.nih.gov/pubmed/36883326
http://dx.doi.org/10.1021/jacs.2c13644