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Ellagic acid ameliorates aging-induced renal oxidative damage through upregulating SIRT1 and NRF2

BACKGROUND: Aging is associated with impaired renal function and structural alterations. Oxidative stress plays a vital role in renal senescence and damage. Sirtuin 1 (SIRT1) is thought to protect cells from oxidative stress through nuclear factor erythroid 2-related factor 2 (NRF2). Ellagic acid (E...

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Detalles Bibliográficos
Autores principales: Naghibi, Niloufar, Sadeghi, Asie, Movahedinia, Sajjadeh, Rahimi Naiini, Mahdis, Rajizadeh, Mohammad Amin, Bahri, Faegheh, Nazari-Robati, Mahdieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999491/
https://www.ncbi.nlm.nih.gov/pubmed/36899375
http://dx.doi.org/10.1186/s12906-023-03907-y