GPR116 receptor regulates the antitumor function of NK cells via Gαq/HIF1α/NF-κB signaling pathway as a potential immune checkpoint

BACKGROUND: NK cell is one of innate immune cells and can protect the body from cancer-initiating cells. It has been reported that GPR116 receptor is involved in inflammation and tumors. However, the effect of GPR116 receptor on the NK cells remains largely unclear. RESULTS: We discovered that GPR11...

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Detalles Bibliográficos
Autores principales: Guo, Dandan, Jin, Chenxu, Gao, Yaoxin, Lin, Haizhen, Zhang, Li, Zhou, Ying, Yao, Jie, Duan, Yixin, Ren, Yaojun, Hui, Xinhui, Ge, Yujia, Yang, Renzheng, Jiang, Wenzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999509/
https://www.ncbi.nlm.nih.gov/pubmed/36895027
http://dx.doi.org/10.1186/s13578-023-01005-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999509/
https://www.ncbi.nlm.nih.gov/pubmed/36895027
http://dx.doi.org/10.1186/s13578-023-01005-7

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