ISL1 controls pancreatic alpha cell fate and beta cell maturation

BACKGROUND: Glucose homeostasis is dependent on functional pancreatic α and ß cells. The mechanisms underlying the generation and maturation of these endocrine cells remain unclear. RESULTS: We unravel the molecular mode of action of ISL1 in controlling α cell fate and the formation of functional ß...

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Detalles Bibliográficos
Autores principales: Bohuslavova, Romana, Fabriciova, Valeria, Lebrón-Mora, Laura, Malfatti, Jessica, Smolik, Ondrej, Valihrach, Lukas, Benesova, Sarka, Zucha, Daniel, Berkova, Zuzana, Saudek, Frantisek, Evans, Sylvia M, Pavlinkova, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999528/
https://www.ncbi.nlm.nih.gov/pubmed/36899442
http://dx.doi.org/10.1186/s13578-023-01003-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999528/
https://www.ncbi.nlm.nih.gov/pubmed/36899442
http://dx.doi.org/10.1186/s13578-023-01003-9

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