Alpha-2-macroglobulin is involved in the occurrence of early-onset pre-eclampsia via its negative impact on uterine spiral artery remodeling and placental angiogenesis

BACKGROUND: Pre-eclampsia (PE) is one of the leading causes of maternal and fetal morbidity/mortality during pregnancy, and alpha-2-macroglobulin (A2M) is associated with inflammatory signaling; however, the pathophysiological mechanism by which A2M is involved in PE development is not yet understoo...

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Detalles Bibliográficos
Autores principales: Wang, Jingyun, Zhang, Ping, Liu, Mengyuan, Huang, Zhengrui, Yang, Xiaofeng, Ding, Yuzhen, Liu, Jia, Cheng, Xin, Xu, Shujie, He, Meiyao, Zhang, Fengxiang, Wang, Guang, Li, Ruiman, Yang, Xuesong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999529/
https://www.ncbi.nlm.nih.gov/pubmed/36894970
http://dx.doi.org/10.1186/s12916-023-02807-9

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