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Calreticulin Immunohistochemistry in Myeloproliferative Neoplasms - Evolution of a New Cost-Effective Diagnostic Tool: A Retrospective Study with Histological and Molecular Correlation

Objective:  Recent WHO 2017 guidelines mandates mutational analysis for the diagnosis of myeloproliferative disorders (MPN). JAK2V617F has been found in only 50-60% of Primary myelofibrosis (PMF) and Essential thrombocythaemia (ET). A recently discovered somatic Calreticulin (CALR) mutation has been...

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Detalles Bibliográficos
Autores principales: Roy, Sanjeet, Manipadam, Marie Therese, Balasubramanian, Poonkuzhali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of Turkish Pathology Societies 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999704/
https://www.ncbi.nlm.nih.gov/pubmed/34514582
http://dx.doi.org/10.5146/tjpath.2021.01550