“…Infertility is a major global health issue and is associated with significant psychological distress for afflicted couples. In vitro fertilisation (IVF) utilises supra-physiological doses of stimulatory hormones to induce the growth of multiple ovarian follicles to enable surgical retrieval of several oocytes for subsequent fertilisation and implantation into the maternal endometrium. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…INTRODUCTION: Ovarian Hyperstimulation Syndrome (OHSS) is a life-threatening iatrogenic complication of In vitro fertilisation (IVF). This study aimed to quantify rates of Ovarian Hyperstimulation Syndrome (OHSS) requiring intensive care unit (ICU) admission and assess whether trends have changed between 1996-2020 commensurate with the introduction of safer IVF practices. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…A subcutaneous bolus of the native form of kisspeptin (kisspeptin-54; KP54) induces an LH-surge lasting 12-14hrs, to safely mature oocytes during in vitro fertilisation (IVF) treatment. The kisspeptin analogue, MVT-602, has a longer half-life (t(1/2) 1.5-2.2h) than native KP54 (t(1/2) 0.5h), which could therefore confer significant advantages as an oocyte maturation trigger in the treatment of infertility. …”
Enlace del recurso
Enlace del recurso