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  1. 1
    “…Laboratories in Leeds and Cardiff will perform the molecular testing. The results of a rigorous pre-trial inter-laboratory analytical validation are presented and discussed. …”
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    Pre-trial inter-laboratory analytical validation of the FOCUS4 personalised therapy trial
  2. 2
    “…Molecular profiling of patients’ formalin-fixed, paraffin-embedded tumour blocks was undertaken at two centralised biomarker laboratories (Leeds and Cardiff), and the results fed directly to the Medical Research Council Clinical Trials Unit, and used for subsequent randomisation. …”
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    FOCUS4 biomarker laboratories: from the benefits to the practical and logistical issues faced during 6 years of centralised testing
  3. 3
    “…ETHICS AND DISSEMINATION: Ethical approval was obtained (REF SMREC 21/59, Cardiff University School of Medicine Research Ethics Committee). …”
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    Development of a core outcome set and identification of patient-reportable outcomes for primary brain tumour trials: protocol for the COBra study
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