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1“…Additionally, applications of these concepts are brought to light in the study of the dynamics of complex systems. The first chapter prepares the basics for the next chapters. …”
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2por Iftime, Manuela Maria, Dobreci, Daniel Lucian, Irimiciuc, Stefan Andrei, Agop, Maricel, Petrescu, Tudor, Doroftei, Bogdan“…The drug release mechanism was firstly assessed by fitting the in vitro release data on five traditional mathematical model. In the context of pharmacokinetics behavioral analysis, a new mathematical procedure for describing drug release dynamics in polymer-drug complex systems was proposed. …”
Publicado 2020
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3por Marin, Luminita, Popa, Marcel, Anisiei, Alexandru, Irimiciuc, Stefan-Andrei, Agop, Maricel, Petrescu, Tudor-Cristian, Vasincu, Decebal, Himiniuc, Loredana“…The theoretical model was developed starting from the hypothesis that the imine-chitosan system, both structurally and functionally, can be assimilated, from a mathematical point of view, with a multifractal object, and its dynamics were analyzed in the framework of the Scale Relativity Theory. …”
Publicado 2021
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4por Ailincai, Daniela, Dorobanțu, Alexandra Maria, Dima, Bogdan, Irimiciuc, Ștefan Andrei, Lupașcu, Cristian, Agop, Maricel, Olguta, Orzan“…An estimation of the drug release kinetics was performed by fitting three traditional mathematical models on experimental release data. Further, the drug delivery was simulated by the fractal theory of motion, in which the release dynamics of the polymer-drug complex system is described through various Riccati-type “regimes.” …”
Publicado 2020
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5por Craciun, Anda-Mihaela, Barhalescu, Mihaela Luminita, Agop, Maricel, Ochiuz, Lăcrămioara“…Drug release is a complex phenomenon due to the large number of interdependent side effects that occur simultaneously, involving strong nonlinear dynamics. Therefore, since their theoretical description is difficult in the classical mathematics modelling, we have built a theoretical model based on logistic type laws, validated by the correlations with the experimental data, in a special case of drug release from hydrogels. …”
Publicado 2019
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6por Ailincai, Daniela, Agop, Maricel, Marinas, Ioana Cristina, Zala, Andrei, Irimiciuc, Stefan Andrei, Dobreci, Lucian, Petrescu, Tudor-Cristian, Volovat, Constantin“…The present paper is a continuation of the work ‘A theoretical mathematical model for assessing diclofenac release from chitosan-based formulations,’ published in Drug Delivery Journal, 27(1), 2020, that focused on the consequences induced by the invariance groups of Multifractal Diffusion Equations in correlation with the drug release dynamics.…”
Publicado 2021
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7por Himiniuc, Loredana, Socolov, Razvan, Ghizdovat, Vlad, Agop, Maricel, Anton, Emil, Toma, Bogdan, Ochiuz, Lacramioara, Vasincu, Decebal, Popa, Ovidiu, Onofrei, Viviana“…The development of the mathematical model considers the release dynamic of the aldehyde in the scale space. …”
Publicado 2022
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