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1por Valcour, Victor G., Spudich, Serena S., Sailasuta, Napapon, Phanuphak, Nittaya, Lerdlum, Sukalaya, Fletcher, James L. K., Kroon, Eugene D. M. B., Jagodzinski, Linda L., Allen, Isabel E., Adams, Collin L., Prueksakaew, Peeriya, Slike, Bonnie M., Hellmuth, Joanna M., Kim, Jerome H., Ananworanich, Jintanat“…OBJECTIVE: To compare central nervous system (CNS) outcomes in participants treated during acute HIV infection with standard combination antiretroviral therapy (cART) vs. cART plus integrase inhibitor and CCR5 antagonist (cART+). …”
Publicado 2015
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2por Valcour, Victor G., Ananworanich, Jintanat, Agsalda, Melissa, Sailasuta, Napapon, Chalermchai, Thep, Schuetz, Alexandra, Shikuma, Cecilia, Liang, Chin-Yuan, Jirajariyavej, Supunee, Sithinamsuwan, Pasiri, Tipsuk, Somporn, Clifford, David B., Paul, Robert, Fletcher, James L. K., Marovich, Mary A., Slike, Bonnie M., DeGruttola, Victor, Shiramizu, Bruce“…OBJECTIVES: Cognitive impairment remains frequent in HIV, despite combination antiretroviral therapy (cART). Leading theories implicate peripheral monocyte HIV DNA reservoirs as a mechanism for spread of the virus to the brain. …”
Publicado 2013
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3por Valcour, Victor G., Ananworanich, Jintanat, Agsalda, Melissa, Sailasuta, Napapon, Chalermchai, Thep, Schuetz, Alexandra, Shikuma, Cecilia, Liang, Chin-Yuan, Jirajariyavej, Supunee, Sithinamsuwan, Pasiri, Tipsuk, Somporn, Clifford, David B., Paul, Robert, Fletcher, James L. K., Marovich, Mary A., Slike, Bonnie M., DeGruttola, Victor, Shiramizu, BruceEnlace del recurso
Publicado 2014
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4por Ananworanich, Jintanat, Chomont, Nicolas, Eller, Leigh Ann, Kroon, Eugene, Tovanabutra, Sodsai, Bose, Meera, Nau, Martin, Fletcher, James L.K., Tipsuk, Somporn, Vandergeeten, Claire, O'Connell, Robert J., Pinyakorn, Suteeraporn, Michael, Nelson, Phanuphak, Nittaya, Robb, Merlin L.“…There was a marked divergence of HIV DNA values between the untreated and treated groups that occurred within the first 2 weeks of ART and increased with time. ART reduced total HIV DNA levels by 20-fold after 2 weeks and 316-fold after 3 years. …”
Publicado 2016
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5por Do, Tanya C, Kerr, Stephen J, Avihingsanon, Anchalee, Suksawek, Saowaluk, Klungkang, Supalak, Channgam, Taweesak, Odermatt, Christoph C, Maek-a-nantawat, Wirach, Ruxtungtham, Kiat, Ananworanich, Jintanat, Valcour, Victor, Reiss, Peter, Wit, Ferdinand W“…RESULTS: HIV-positive participants, mean age 45 (SD 7.69) years received cART for a median of 12.1 years (interquartile range [IQR] 9.1–14.4). …”
Publicado 2018
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6por Hsu, Denise C., Kerr, Stephen J., Iampornsin, Thatri, Pett, Sarah L., Avihingsanon, Anchalee, Thongpaeng, Parawee, Zaunders, John J., Ubolyam, Sasiwimol, Ananworanich, Jintanat, Kelleher, Anthony D., Cooper, David A.“…METHODS: Fifty HIV-infected, ART-naïve Thai adults with CD4 T cell count ≤350cells/µL and starting ART were evaluated over 96 weeks (ClinicalTrials.gov identifier NCT01296373). …”
Publicado 2013
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7por Kroon, Eugène, Chottanapund, Suthat, Buranapraditkun, Supranee, Sacdalan, Carlo, Colby, Donn J, Chomchey, Nitiya, Prueksakaew, Peeriya, Pinyakorn, Suteeraporn, Trichavaroj, Rapee, Vasan, Sandhya, Manasnayakorn, Sopark, Reilly, Cavan, Helgeson, Erika, Anderson, Jodi, David, Caitlin, Zulk, Jacob, de Souza, Mark, Tovanabutra, Sodsai, Schuetz, Alexandra, Robb, Merlin L, Douek, Daniel C, Phanuphak, Nittaya, Haase, Ashley, Ananworanich, Jintanat, Schacker, Timothy W“…Starting antiretroviral therapy (ART) in Fiebig 1 acute HIV infection limits the size of viral reservoirs in lymphoid tissues, but does not impact time to virus rebound during a treatment interruption. …”
Publicado 2022
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8por Schuetz, Alexandra, Deleage, Claire, Sereti, Irini, Rerknimitr, Rungsun, Phanuphak, Nittaya, Phuang-Ngern, Yuwadee, Estes, Jacob D., Sandler, Netanya G., Sukhumvittaya, Suchada, Marovich, Mary, Jongrakthaitae, Surat, Akapirat, Siriwat, Fletscher, James L. K., Kroon, Eugene, Dewar, Robin, Trichavaroj, Rapee, Chomchey, Nitiya, Douek, Daniel C., O′Connell, Robert J., Ngauy, Viseth, Robb, Merlin L., Phanuphak, Praphan, Michael, Nelson L., Excler, Jean-Louis, Kim, Jerome H., de Souza, Mark S., Ananworanich, Jintanat“…Furthermore, early initiation of ART in FI/II fully reversed the initially observed mucosal and systemic immune-activation. …”
Publicado 2014
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9“…With limited funds to provide ART to millions of patients worldwide, there is a need for alternative ways to scale up ART in resource limited settings. …”
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10por Kroon, Eugène D.M.B., Ananworanich, Jintanat, Pagliuzza, Amélie, Rhodes, Ajantha, Phanuphak, Nittaya, Trautmann, Lydie, Mitchell, Julie L., Chintanaphol, Michelle, Intasan, Jintana, Pinyakorn, Suteeraporn, Benjapornpong, Khuntalee, Chang, J. Judy, Colby, Donn J., Chomchey, Nitiya, Fletcher, James L.K., Eubanks, Keith, Yang, Hua, Kapson, John, Dantanarayana, Ashanti, Tennakoon, Surekha, Gorelick, Robert J., Maldarelli, Frank, Robb, Merlin L., Kim, Jerome H., Spudich, Serena, Chomont, Nicolas, Phanuphak, Praphan, Lewin, Sharon R., de Souza, Mark S.“…METHODS: Fifteen participants who initiated ART at AHI were randomized to vorinostat/hydroxychloroquine/maraviroc (VHM) plus ART (n = 10) or ART alone (n = 5). …”
Publicado 2020
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11por Jantarabenjakul, Watsamon, Chonchaiya, Weerasak, Puthanakit, Thanyawee, Theerawit, Tuangtip, Payapanon, Jesdaporn, Sophonphan, Jiratchaya, Veeravigom, Montida, Jahanshad, Neda, Thompson, Paul M, Ananworanich, Jintanat, Malee, Kathleen, Pancharoen, Chitsanu“…INTRODUCTION: Antiretroviral therapy (ART) is recommended in perinatally HIV‐infected (PHIV) infants immediately upon diagnosis. …”
Publicado 2019
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12por Mitchell, Julie L., Pollara, Justin, Dietze, Kenneth, Edwards, R. Whitney, Nohara, Junsuke, N’guessan, Kombo F., Zemil, Michelle, Buranapraditkun, Supranee, Takata, Hiroshi, Li, Yifan, Muir, Roshell, Kroon, Eugene, Pinyakorn, Suteeraporn, Jha, Shalini, Manasnayakorn, Sopark, Chottanapund, Suthat, Thantiworasit, Pattarawat, Prueksakaew, Peeriya, Ratnaratorn, Nisakorn, Nuntapinit, Bessara, Fox, Lawrence, Tovanabutra, Sodsai, Paquin-Proulx, Dominic, Wieczorek, Lindsay, Polonis, Victoria R., Maldarelli, Frank, Haddad, Elias K., Phanuphak, Praphan, Sacdalan, Carlo P., Rolland, Morgane, Phanuphak, Nittaya, Ananworanich, Jintanat, Vasan, Sandhya, Ferrari, Guido, Trautmann, Lydie“…Early initiation of antiretroviral therapy (ART) in acute HIV infection (AHI) is effective at limiting seeding of the HIV viral reservoir, but little is known about how the resultant decreased antigen load affects long-term Ab development after ART. …”
Publicado 2022
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13por Ananworanich, Jintanat, Kerr, Stephen J, Jaimulwong, Tanyathip, Vibol, Ung, Hansudewechakul, Rawiwan, Kosalaraksa, Pope, Ngampiyaskul, Chaiwat, Kanjanavanit, Suparat, Wongsawat, Jurai, Luesomboon, Wicharn, Apornpong, Tanakorn, Soulas, Caroline, Paul, Robert, Ruxrungtham, Kiat, Puthanakit, Thanyawee“…OBJECTIVE: To determine the relationship between monocyte subsets, the sCD163 monocyte activation marker, and neuropsychological performance among perinatally HIV-infected children initiating antiretroviral therapy (ART). METHODS: ART-naïve children from the PREDICT study were categorised into two groups: those on ART for ≥24 weeks (ART group, n=201) and those untreated (no ART group, n=79). …”
Publicado 2015
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14por Takata, Hiroshi, Kakazu, Juyeon C., Mitchell, Julie L., Kroon, Eugene, Colby, Donn J., Sacdalan, Carlo, Bai, Hongjun, Ehrenberg, Philip K., Geretz, Aviva, Buranapraditkun, Supranee, Pinyakorn, Suteeraporn, Intasan, Jintana, Tipsuk, Somporn, Suttichom, Duanghathai, Prueksakaew, Peeriya, Chalermchai, Thep, Chomchey, Nitiya, Phanuphak, Nittaya, de Souza, Mark, Michael, Nelson L., Robb, Merlin L., Haddad, Elias K., Crowell, Trevor A, Vasan, Sandhya, Valcour, Victor G., Douek, Daniel C., Thomas, Rasmi, Rolland, Morgane, Chomont, Nicolas, Ananworanich, Jintanat, Trautmann, Lydie“…Although HIV-specific CD8(+) T cells become dysfunctional without treatment, antiretroviral therapy (ART) partially restores their function. However, the extent of this recovery under long-term ART is less understood. …”
Publicado 2022
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15por Handoko, Ryan, Colby, Donn J, Kroon, Eugène, Sacdalan, Carlo, de Souza, Mark, Pinyakorn, Suteeraporn, Prueksakaew, Peeriya, Munkong, Chutharat, Ubolyam, Sasiwimol, Akapirat, Siriwat, Chiarella, Jennifer, Krebs, Shelly, Sereti, Irini, Valcour, Victor, Paul, Robert, Michael, Nelson L., Phanuphak, Nittaya, Ananworanich, Jintanat, Spudich, Serena“…INTRODUCTION: Up to 30% of individuals treated with antiretroviral therapy (ART) during chronic HIV fail to recover CD4 counts to >500 cells/mm(3) despite plasma viral suppression. …”
Publicado 2020
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16por Kancheva Landolt, Nadia, Bunupuradah, Torsak, Achalapong, Jullapong, Kosalaraksa, Pope, Petdachai, Witaya, Ngampiyaskul, Chaiwat, Ubolyam, Sasiwimol, Thammajaruk, Narukjaporn, Kerr, Stephen, Ananworanich, Jintanat“…METHODS: We conducted a cross-sectional assessment of markers for carbohydrate, lipid, bone metabolism, inflammation and coagulation in HIV-positive adolescents on ART and HC (n=37) versus on ART only (n=51) in Thailand. …”
Publicado 2017
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17por Han, Win Min, Ubolyam, Sasiwimol, Apornpong, Tanakorn, Kerr, Stephen J., Hansasuta, Pokrath, Gatechompol, Sivaporn, Maekanantawat, Wirach, Ruxrungtham, Kiat, Phanuphak, Praphan, Ananworanich, Jintanat, Avihingsanon, Anchalee“…RESULTS: Among 375 participants with pre-ART CD4 T cell counts < 200 cells/mm(3), the prevalence of SIR was 39.7%, 19.7% and 7.7% at years 1, 2 and 3 after starting ART, respectively. …”
Publicado 2020
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18por Ananworanich, Jintanat, Kosalaraksa, Pope, Siangphoe, Umaporn, Engchanil, Chulapan, Pancharoen, Chitsanu, Lumbiganon, Pagakrong, Intasan, Jintana, Apateerapong, Wichitra, Chuenyam, Theshinee, Ubolyam, Sasiwimol, Bunupuradah, Torsak, Lange, Joep, Cooper, David A, Phanuphak, Praphan“…All accepted the randomized arm; however, 3 in arm 1 stopped ART and 1 in arm 2 refused to start ART. Ten/19 (53%) in arm 2 started ART. …”
Publicado 2008
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19por Kroon, Eugène D.M.B., Phanuphak, Nittaya, Shattock, Andrew J., Fletcher, James L.K., Pinyakorn, Suteeraporn, Chomchey, Nitiya, Akapirat, Siriwat, de Souza, Mark S., Robb, Merlin L., Kim, Jerome H., van Griensven, Frits, Ananworanich, Jintanat, Wilson, David P.“…Introduction: Antiretroviral treatment (ART) reduces HIV transmission. Despite increased ART coverage, incidence remains high among men who have sex with men (MSM) in many places. …”
Publicado 2017
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20por Paul, Robert, Cho, Kyu, Bolzenius, Jacob, Sacdalan, Carlo, Ndhlovu, Lishomwa C., Trautmann, Lydie, Krebs, Shelly, Tipsuk, Somporn, Crowell, Trevor A., Suttichom, Duanghathai, Colby, Donn J., Premeaux, Thomas A., Phanuphak, Nittaya, Chan, Phillip, Kroon, Eugène, Vasan, Sandhya, Hsu, Denise, Carrico, Adam, Valcour, Victor, Ananworanich, Jintanat, Robb, Merlin L., Ake, Julie A., Sriplienchan, Somchai, Spudich, Serena“…OBJECTIVE: We examined individual differences in CD4/CD8 T-cell ratio trajectories and associated risk profiles from acute HIV infection (AHI) through 144 weeks of antiretroviral therapy (ART) using a data-driven approach. METHODS: A total of 483 AHI participants began ART during Fiebig I–V and completed follow-up evaluations for 144 weeks. …”
Publicado 2022
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