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  1. 1
    “…We examined three metrics of infection and disease in a pediatric cohort (N≈3,000) over two chikungunya and one Zika epidemic, and in a household cohort (N=1,793) over one COVID-19 epidemic in Managua, Nicaragua. We compared spatial incidence rates (cases/total population), infection risks (infections/total population), and disease risks (cases/infected population). …”
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    Epidemics of chikungunya, Zika, and COVID-19 reveal bias in case-based mapping
  2. 2
    “…METHODS: We conducted a household cohort study from March 2020-November 2022 in Managua, Nicaragua; following a housheold SARS-CoV-2 infection, household members are closely monitored for infection. …”
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    Infection-Induced Immunity Is Associated With Protection Against Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Decreased Infectivity
  3. 3
    “…METHODS: We conducted a household cohort study between March 2020-June 2022 in Managua, Nicaragua where when one household member tests positive for SARS-CoV-2, household members are closely monitored for SARS-CoV-2 infection. …”
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    Infection-induced immunity is associated with protection against SARS-CoV-2 infection, but not decreased infectivity during household transmission
  4. 4
    “…METHODS: We conducted a household cohort study in Managua, Nicaragua, with an embedded transmission study that closely monitors participants regardless of symptoms. …”
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    SARS‐CoV‐2 infection‐induced immunity and the duration of viral shedding: Results from a Nicaraguan household cohort study
  5. 5
    “…METHODS: We followed 2338 people in Managua, Nicaragua, aged <94 years from March 2020 through March 2021. …”
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    Clinical Spectrum of Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Protection From Symptomatic Reinfection
  6. 6
    “…DESIGN, SETTING, AND PARTICIPANTS: In this prospective, community-based pediatric cohort study conducted from March 1, 2020, to October 15, 2021, 1964 nonimmunocompromised children aged 0 to 14 years were enrolled by random selection from the Nicaraguan Pediatric Influenza Cohort, a community-based cohort in District 2 of Managua, Nicaragua. Additional newborn infants aged 4 weeks or younger were randomly selected and enrolled monthly via home visits. …”
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    Association of SARS-CoV-2 Seropositivity and Symptomatic Reinfection in Children in Nicaragua
  7. 7
    “…SETTING: The Nicaraguan Pediatric Influenza Cohort is a community-based cohort in District 2 of Managua, Nicaragua. PARTICIPANTS: A total of 1964 children aged 0–14 years participated in the cohort. …”
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    Burden of SARS-CoV-2 and protection from symptomatic second infection in children
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