Mostrando 1 - 13 Resultados de 13 Para Buscar '"mural"', tiempo de consulta: 0.14s Limitar resultados
  1. 1
    “…Pericytes, the mural cells of blood microvessels, regulate microvascular development and function and have been implicated in many brain diseases. …”
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    Analysis of the brain mural cell transcriptome
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    “…Pericytes and vascular smooth muscle cells, collectively known as mural cells, are recruited through PDGFB (platelet-derived growth factor B)-PDGFRB (platelet-derived growth factor receptor beta) signaling. …”
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    Mural Cell SRF Controls Pericyte Migration, Vessel Patterning and Blood Flow
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    “…We reveal gene expression signatures that demarcate fibroblasts from mural cells and provide molecular signatures for cell subtype identification. …”
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    Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination
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    “…We observed that emergence of mural cells around the intersegmental arteries coincides with lymphatic departure from HM which raised the possibility that arterial mural cells promote LEC migration. …”
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    Proper migration of lymphatic endothelial cells requires survival and guidance cues from arterial mural cells
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    Correction: Proper migration of lymphatic endothelial cells requires survival and guidance cues from arterial mural cells
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    Publisher Correction: Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination
  7. 7
    “…Apart from their endocrine functions renin-expressing cells play an important functional role as mural cells of the developing preglomerular arteriolar vessel tree in the kidney. …”
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    Development of renal renin-expressing cells does not involve PDGF-B-PDGFR-β signaling
  8. 8
    por Betsholtz, Christer
    Publicado 2018
    “…Over the past decades, we have learnt about the generic cell–cell signaling mechanisms governing angiogenic sprouting, mural cell recruitment, and vascular remodeling, and we have obtained the first insights into signals that induce and maintain vascular organotypicity. …”
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    Cell–cell signaling in blood vessel development and function
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    “…Using high-resolution imaging, we show that lymphoid tissue inducer (LTi) cells initially transmigrate from veins at LN development sites using gaps in venous mural coverage. This process is independent of lymphatic vasculature, but lymphatic vessels are indispensable for the transport of LTi cells that egress from blood capillaries elsewhere and serve as an essential LN expansion reservoir. …”
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    Multiple roles of lymphatic vessels in peripheral lymph node development
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    “…Endothelial cells appeared to be the dominating source for Pdgfd, but reporter gene activity was occasionally also found in subpopulations of mural cells. Tissue-specific analyses of vascular structures revealed that NG2-expressing pericytes of the cardiac vasculature were disorganized in Pdgfd(-/-) mice. …”
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    Mice Lacking Platelet-Derived Growth Factor D Display a Mild Vascular Phenotype
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    por Betsholtz, Christer
    Publicado 2022
    “…These, in turn, are dictated by differential gene expression by the two principal cellular building blocks of blood vessels: endothelial cells and mural cells. An organotypic vasculature is essential for functions as diverse as thinking, gas exchange, urine excretion, and xenobiotic detoxification in the brain, lung, kidney, and liver, respectively. …”
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    Toward a granular molecular-anatomic map of the blood vasculature – single-cell RNA sequencing makes the leap
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    “…In conclusion, we demonstrate that reduced Notch3 or PDGFB signalling in vascular mural cells leads to cardiomyocyte dysfunction.…”
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    Left ventricular hypertrophy and metabolic resetting in the Notch3-deficient adult mouse heart
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    “…Importantly, we detect heterogeneity in glomerulus-associated Pdgfrb-expressing cells, including bona fide intraglomerular MCs with the functionally active phagocytic molecular machinery, as well as a unique mural cell type located in the central stalk region of the glomerulus tuft. …”
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    Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes
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