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1Hypoxia-altitude simulation test to predict altitude-related adverse health effects in COPD patientspor Bauer, Meret, Müller, Julian, Schneider, Simon R., Buenzli, Simone, Furian, Michael, Ulrich, Tanja, Carta, Arcangelo F., Bader, Patrick R., Lichtblau, Mona, Taalaibekova, Ajian, Raimberdiev, Madiiar, Champigneulle, Benoit, Sooronbaev, Talant, Bloch, Konrad E., Ulrich, Silvia“…BACKGROUND/AIMS: Amongst numerous travellers to high altitude (HA) are many with the highly prevalent COPD, who are at particular risk for altitude-related adverse health effects (ARAHE). …”
Publicado 2023
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2por Barthelmes, Daniel, Bosch, Martina M., Merz, Tobias M., Petrig, Benno L., Truffer, Frederic, Bloch, Konrad E., Holmes, Timothy A., Cattin, Philippe, Hefti, Urs, Sellner, Miriam, Sutter, Florian K. P., Maggiorini, Marco, Landau, Klara“…BACKGROUND: Retinal hemorrhages have been described as a component of high altitude retinopathy (HAR) in association with altitude illness. …”
Publicado 2011
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3por Bloch, Konrad E., Sooronbaev, Talant M., Ulrich, Silvia, Lichtblau, Mona, Furian, Michael“…In addition, hypobaric hypoxia may impair postural control, psycho-motor, and cognitive performance in patients with COPD during altitude sojourns. Randomized, placebo-controlled trials have shown that preventive treatment with oxygen at night or with acetazolamide reduces the risk of ARAHE in patients with COPD while preventive dexamethasone treatment improves oxygenation and altitude-induced excessive sleep apnea, and lowers systemic and pulmonary artery pressure. …”
Publicado 2023
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4por Pun, Matiram, Guadagni, Veronica, Bettauer, Kaitlyn M., Drogos, Lauren L., Aitken, Julie, Hartmann, Sara E., Furian, Michael, Muralt, Lara, Lichtblau, Mona, Bader, Patrick R., Rawling, Jean M., Protzner, Andrea B., Ulrich, Silvia, Bloch, Konrad E., Giesbrecht, Barry, Poulin, Marc J.“…Objective: Neurocognitive functions are affected by high altitude, however the altitude effects of acclimatization and repeated exposures are unclear. …”
Publicado 2018
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5por Furian, Michael, Bitos, Konstantinos, Hartmann, Sara E., Muralt, Lara, Lichtblau, Mona, Bader, Patrick R., Rawling, Jean M., Ulrich, Silvia, Poulin, Marc J., Bloch, Konrad E.“…We hypothesized that prolonged and repeated high-altitude exposure will improve altitude-induced deoxygenation and breathing instability. …”
Publicado 2022
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6por Clarenbach, Christian F., Senn, Oliver, Christ, Andreas L., Fischler, Manuel, Maggiorini, Marco, Bloch, Konrad E.“…INTRODUCTION: The purpose of the study was to comprehensively evaluate physiologic changes associated with development of high altitude pulmonary edema (HAPE). We tested whether changes in pulmonary function and breathing pattern would herald clinically overt HAPE at an early stage. …”
Publicado 2012
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7por Stöwhas, Anne-Christin, Latshang, Tsogyal D., Lo Cascio, Christian M., Lautwein, Sina, Stadelmann, Katrin, Tesler, Noemi, Ayers, Lisa, Berneis, Kaspar, Gerber, Philipp A., Huber, Reto, Achermann, Peter, Bloch, Konrad E., Kohler, Malcolm“…However, the effects of acute exposure to moderate altitude on the cardiovascular system and metabolism are largely unknown. …”
Publicado 2013
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8por Stadelmann, Katrin, Latshang, Tsogyal D., Lo Cascio, Christian M., Tesler, Noemi, Stoewhas, Anne-Christin, Kohler, Malcolm, Bloch, Konrad E., Huber, Reto, Achermann, Peter“…BACKGROUND: Previous studies have observed an altitude-dependent increase in central apneas and a shift towards lighter sleep at altitudes >4000 m. …”
Publicado 2013
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9por Saxer, Stéphanie, Schneider, Simon R., Appenzeller, Paula, Bader, Patrick R., Lichtblau, Mona, Furian, Michael, Sheraliev, Ulan, Estebesova, Bermet, Emilov, Berik, Sooronbaev, Talant, Bloch, Konrad E., Ulrich, Silvia“…BACKGROUND: To investigate the effect of asthma rehabilitation at high altitude (3100 m, HA) compared to low altitude (760 m, LA). …”
Publicado 2019
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10por Fieten, Karin B., Drijver‐Messelink, Marieke T., Cogo, Annalisa, Charpin, Denis, Sokolowska, Milena, Agache, Ioana, Taborda‐Barata, Luís Manuel, Eguiluz‐Gracia, Ibon, Braunstahl, Gerrit J., Seys, Sven F., van den Berge, Maarten, Bloch, Konrad E., Ulrich, Silvia, Cardoso‐Vigueros, Carlos, Kappen, Jasper H., Brinke, Anneke ten, Koch, Markus, Traidl‐Hoffmann, Claudia, da Mata, Pedro, Prins, David J., Pasmans, Suzanne G. M. A., Bendien, Sarah, Rukhadze, Maia, Shamji, Mohamed H., Couto, Mariana, Oude Elberink, Hanneke, Peroni, Diego G., Piacentini, Giorgio, Weersink, Els J. M., Bonini, Matteo, Rijssenbeek‐Nouwens, Lucia H. M., Akdis, Cezmi A.“…Currently available European Alpine Altitude Climate Treatment (AACT) programs combine the physical characteristics of altitude with the avoidance of environmental triggers in the alpine climate and a personalized multidisciplinary pulmonary rehabilitation approach. …”
Publicado 2022
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11por Pun, Matiram, Hartmann, Sara E., Furian, Michael, Dyck, Adrienna M., Muralt, Lara, Lichtblau, Mona, Bader, Patrick R., Rawling, Jean M., Ulrich, Silvia, Bloch, Konrad E., Poulin, Marc J.“…Aim: High altitude (HA) hypoxia may affect cognitive performance and sleep quality. …”
Publicado 2018
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12por Lichtblau, Mona, Saxer, Stéphanie, Latshang, Tsogyal D., Aeschbacher, Sayaka S., Huber, Fabienne, Scheiwiller, Philipp M., Herzig, Joël J., Schneider, Simon R., Hasler, Elisabeth D., Furian, Michael, Bloch, Konrad E., Ulrich, Silvia“…Introduction: Stable patients with pulmonary arterial or chronic thromboembolic pulmonary hypertension (PH) wish to undergo altitude sojourns or air travel but fear disease worsening. …”
Publicado 2020
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13Validation of a Portable Blood Gas Analyzer for Use in Challenging Field Conditions at High Altitudepor Nawrocki, Janek, Furian, Michael, Buergin, Aline, Mayer, Laura, Schneider, Simon, Mademilov, Maamed, Bloch, Madeleine S., Sooronbaev, Talant M., Ulrich, Silvia, Bloch, Konrad E.“…METHODS: In healthy individuals and patients with chronic obstructive pulmonary disease participating in clinical field studies at different altitudes, arterial blood samples were obtained at rest and during exercise in a hospital at 760 m and in a high altitude clinic at 3100 m. …”
Publicado 2021
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14por Schneider, Simon R., Lichtblau, Mona, Furian, Michael, Mayer, Laura C., Berlier, Charlotte, Müller, Julian, Saxer, Stéphanie, Schwarz, Esther I., Bloch, Konrad E., Ulrich, Silvia“…Prediction of adverse health effects at altitude or during air travel is relevant, particularly in pre-existing cardiopulmonary disease such as pulmonary arterial or chronic thromboembolic pulmonary hypertension (PAH/CTEPH, PH). …”
Publicado 2022
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15por Reiser, Aurelia E., Furian, Michael, Lichtblau, Mona, Buergin, Aline, Schneider, Simon R., Appenzeller, Paula, Mayer, Laura, Muralt, Lara, Mademilov, Maamed, Abdyraeva, Ainura, Aidaralieva, Shoira, Muratbekova, Aibermet, Akylbekov, Azamat, Sheraliev, Ulan, Shabykeeva, Saltanat, Sooronbaev, Talant M., Ulrich, Silvia, Bloch, Konrad E.“…OBJECTIVE: Altitude travel is increasingly popular also for middle-aged and older tourists and professionals. …”
Publicado 2023
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16por Schneider, Simon R., Mayer, Laura C., Lichtblau, Mona, Berlier, Charlotte, Schwarz, Esther I., Saxer, Stéphanie, Tan, Lu, Furian, Michael, Bloch, Konrad E., Ulrich, Silvia“…For safety, patients with sustained hypoxaemia at altitude (peripheral oxygen saturation <80% for >30 min or <75% for >15 min) received oxygen therapy. …”
Publicado 2021
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17por Lichtblau, Mona, Saxer, Stéphanie, Mayer, Laura, Sheraliev, Ulan, Mademilov, Maamed, Furian, Michael, Buergin, Aline, Schweiwiller, Philipp M., Schneider, Simon R., Tanner, Felix C., Sooronbaev, Talant, Bloch, Konrad E., Ulrich, Silvia“…BACKGROUND: COPD may predispose to symptomatic pulmonary hypertension at high altitude. We investigated haemodynamic changes in lowlanders with COPD ascending to 3100 m and evaluated whether preventive acetazolamide treatment would attenuate the altitude-induced increase in pulmonary artery pressure (PAP). …”
Publicado 2023
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18por Stadelmann, Katrin, Latshang, Tsogyal D., Lo Cascio, Christian M., Clark, Ross A., Huber, Reto, Kohler, Malcolm, Achermann, Peter, Bloch, Konrad E.“…OBJECTIVES: Intact postural control is essential for safe performance of mountain sports, operation of machinery at altitude, and for piloting airplanes. We tested whether exposure to hypobaric hypoxia at moderate altitude impairs the static postural control of healthy subjects. …”
Publicado 2015
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19por Champigneulle, Benoit, Reinhard, Lukas, Mademilov, Maamed, Marillier, Mathieu, Ulrich, Tanja, Carta, Arcangelo F., Scheiwiller, Philipp, Shabykeeva, Saltanat B., Sheraliev, Ulan U., Abdraeva, Ainura K., Magdieva, Kamila M., Mirzalieva, Gulzada, Taalaibekova, Aijan T., Ozonova, Aigul K., Erkinbaeva, Aidai O., Shakiev, Nurdin U., Azizbekov, Syimyk A., Ainslie, Philip N., Sooronbaev, Talant M., Ulrich, Silvia, Bloch, Konrad E., Verges, Samuel, Furian, Michael“…Concurrent measurements of cPaO(2) (AGM100) and mPaO(2) (EPOC, portable aBGA device) were performed in 131 moderate-to-severe COPD patients (mean ±SD FEV(1): 60 ± 10% of predicted value) and low-altitude residents, becoming hypoxemic (i.e., SpO(2) < 94%) during a short stay at 3100 m (Too-Ashu, Kyrgyzstan). …”
Publicado 2023
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20por Lichtblau, Mona, Latshang, Tsogyal D., Aeschbacher, Sayaka S., Huber, Fabienne, Scheiwiller, Philipp M., Ulrich, Stefanie, Schneider, Simon R., Hasler, Elisabeth D., Furian, Michael, Bloch, Konrad E., Saxer, Stéphanie, Ulrich, Silvia“…INTRODUCTION: We investigated whether nocturnal oxygen therapy (NOT) mitigates the increase of pulmonary artery pressure in patients during daytime with chronic obstructive pulmonary disease (COPD) traveling to altitude. METHODS: Patients with COPD living below 800 m underwent examinations at 490 m and during two sojourns at 2,048 m (with a washout period of 2 weeks < 800 m between altitude sojourns). …”
Publicado 2021
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